FlyBase Allele Report: Dmel\ple[HMC06137]

General Information

Symbol

Dmel\ple^HMC06137

Species

D. melanogaster

Name

FlyBase ID

FBal0322407

Feature type

allele

Associated gene

Dmel\ple

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC06137}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HMC06137}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC06137

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color | adult stage, with Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Phenotype Manifest In

adult external abdomen, with Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

adult external thorax, with Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Detailed Description

Statement

Reference

The expression of ple^HMC06137 under the control of Scer\GAL4^pnr-MD237 induces hypopigmentation in the adult thorax and abdomen.

(Zhang et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

ple^HMC06137, Scer\GAL4^pnr-MD237 is a suppressor of abnormal body color | adult stage phenotype of Rpn9^HMS05753, Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Scer\GAL4^pnr-MD237/ple^HMC06137 is a suppressor of abnormal body color | adult stage phenotype of Scer\GAL4^pnr-MD237, Vhl^KK111257

(Zhang et al., 2021)

ple^HMC06137, Scer\GAL4^0273-G4 is a suppressor | partially of abnormal locomotor behavior | adult stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}, Scer\GAL4^0273-G4

(Stern et al., 2019)

Phenotype Manifest In

Suppressor of

Statement

Reference

ple^HMC06137, Scer\GAL4^pnr-MD237 is a suppressor of adult external thorax phenotype of Rpn9^HMS05753, Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Scer\GAL4^pnr-MD237/ple^HMC06137 is a suppressor of adult external thorax phenotype of Scer\GAL4^pnr-MD237, Vhl^KK111257

(Zhang et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

65875

y¹ sc^* v¹ sev²¹; P{TRiP.HMC06137}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ple^HMC06137

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close