FlyBase Allele Report: Dmel\Dlish[UAS.Tag:FLAG]

General Information

Symbol

Dmel\Dlish^UAS.Tag:FLAG

Species

D. melanogaster

Name

FlyBase ID

FBal0323152

Feature type

allele

Associated gene

Dmel\Dlish

Associated Insertion(s)

Carried in Construct

PBac{UAS-Dlish.FLAG}

Also Known As

UAS-dlish-FLAG

Key Links

Transgenic product class

wild_type

(Zhang et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Zhang et al., 2016)

Mutagen

in vitro construct

(Zhang et al., 2016)

Progenitor genotype

Carried in construct

PBac{UAS-Dlish.FLAG}

Cytology

Description

UAS regulatory sequences drive expression of Dlish tagged with Tag:FLAG.

(Zhang et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Dlish

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^hh-Gal4

(Wang et al., 2019)

abnormal size | late third instar larval stage, with Scer\GAL4^hh-Gal4

(Wang et al., 2019)

hyperplasia | adult stage, with Scer\GAL4^hh.PU

(Zhang et al., 2016)

visible | adult stage, with Scer\GAL4^hh.PU

(Zhang et al., 2016)

visible | adult stage, with Scer\GAL4^hh-Gal4

(Wang et al., 2019)

Phenotype Manifest In

wing disc posterior compartment | late third instar larval stage, with Scer\GAL4^hh-Gal4

(Wang et al., 2019)

wing posterior compartment, with Scer\GAL4^hh.PU

(Zhang et al., 2016)

wing posterior compartment, with Scer\GAL4^hh-Gal4

(Wang et al., 2019)

Detailed Description

Statement

Reference

Expressing Dlish^UAS.Tag:FLAG under the control of Scer\GAL4^hh-Gal4 results in an overgrown posterior compartment in both the wing discs of late third instar larvae and adult wings.

(Wang et al., 2019)

Expression of Dlish^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^hh.PU increases the size of the adult wing posterior compartment compared to controls.

(Zhang et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4 has abnormal size | late third instar larval stage phenotype, non-enhanceable by dachs^GC13/dachs^GC13

(Wang et al., 2019)

NOT suppressed by

Statement

Reference

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4 has abnormal size | late third instar larval stage phenotype, non-suppressible by dachs^GC13/dachs^GC13

(Wang et al., 2019)

Other

Statement

Reference

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4, dachs¹/dachs^GC13 has visible | adult stage phenotype

(Wang et al., 2019)

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4, dachs¹/dachs^GC13 has abnormal size | adult stage phenotype

(Wang et al., 2019)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4 has wing disc posterior compartment | late third instar larval stage phenotype, non-enhanceable by dachs^GC13/dachs^GC13

(Wang et al., 2019)

NOT suppressed by

Statement

Reference

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4 has wing disc posterior compartment | late third instar larval stage phenotype, non-suppressible by dachs^GC13/dachs^GC13

(Wang et al., 2019)

Other

Statement

Reference

Dlish^UAS.Tag:FLAG, Scer\GAL4^hh-Gal4, dachs¹/dachs^GC13 has wing phenotype

(Wang et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Expressing Dlish^UAS.Tag:FLAG under the control of Scer\GAL4^hh-Gal4 in a d¹/d^GC13 background results in an overgrown posterior compartment of an overall smaller wing compared to wild-type controls.

(Wang et al., 2019)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Dlish^{Scer\UAS.T:Zzzz\FLAG}

Dlish^UAS.Tag:FLAG

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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