FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\aubAA.UASp.mGFP6
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General Information
Symbol
Dmel\aubAA.UASp.mGFP6
Species
D. melanogaster
Name
FlyBase ID
FBal0323875
Feature type
allele
Associated gene
Dmel\aub
Associated Insertion(s)
Carried in Construct
P{UASp-GFP-aub.AA}
Also Known As
UASp-GFP-AubAA
Key Links
Transgenic product class
missense_variant
(Barckmann et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Barckmann et al., 2015)
Mutagen
in vitro construct
(Barckmann et al., 2015)
Progenitor genotype
Carried in construct
P{UASp-GFP-aub.AA}
Cytology
Description

UASp regulatory sequences drive expression of a mutant form of aub in which two conserved residues involved in the interaction with piRNAs (residues Y345A and Y346A in the PAZ domain) have been mutated. The protein is tagged at the N-terminal end with mGFP6.

(Barckmann et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
aub
Tagged with
mGFP6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of aubAA.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 does not induce embryonic lethality or dorsal appendages defects in embryos.

      (Barckmann et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4VP16.nanos.UTR/aubAA.UASp.mGFP6 fails to rescue aubHN2/aubQC42

      (Barckmann et al., 2015)
      Comments

      The maternal effect embryonic lethality and dorsal appendages fusion characteristic for embryos from aubHN2/aubQC42 mothers cannot be rescued by expression of aubAA.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in the embryos.

      (Barckmann et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      aubAA.Scer\UAS.P\T.T:Avic\GFP-m6
      aubAA.UASp.mGFP6
      Name Synonyms
      Secondary FlyBase IDs
        References (2)