FB2026_02 , released June 18, 2026
Allele: Dmel\TorsinΔD.UAS
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General Information
Symbol
Dmel\TorsinΔD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0324788
Feature type
allele
Associated gene
Dmel\Torsin
Associated Insertion(s)
Carried in Construct
P{UAS-Torsin.ΔD}
Key Links
Transgenic product class
inframe_deletion
(Wakabayashi-Ito et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Wakabayashi-Ito et al., 2015)
Mutagen
in vitro construct
(Wakabayashi-Ito et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Torsin.ΔD}
Cytology
Description

UASt regulatory sequences drive expression of Torsin in which the conserved amino acid residue D307 has been deleted.

(Wakabayashi-Ito et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Torsin
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PU, TorsinΔD.UAS, TorsinUAS.cWa rescues TorsinKO13

      (Wakabayashi-Ito et al., 2015)

      Scer\GAL4elav.PU/TorsinΔD.UAS rescues TorsinKO13

      (Wakabayashi-Ito et al., 2015)
      Comments

      The deficit in larval locomotion (decreased peristaltic rate) characteristic for TorsinKO13 hemizygous male third instar larvae can be rescued by expression of TorsinΔD.Scer\UAS as well as by combined expression of TorsinScer\UAS.cWa with TorsinΔD.Scer\UAS under the control of Scer\GAL4elav.PU.

      (Wakabayashi-Ito et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TorsinΔD.Scer\UAS
      TorsinΔD.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)