Open Close
General Information
Symbol
Dmel\Opa1UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0325676
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of full-length Opa1 cDNA tagged with 3x-Tag:HA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Opa1Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4109(2)80 results in large spherical mitochondrial morphology as well as shortening of the dendritic arbor in the class IV ddaC neurons in third instar larvae, no significant loss of dendrites is observed in either the class III ddaA neurons (with the Scer\GAL4smid-C161 driver) or in the class I ddaE neurons (with the Scer\GAL4221 driver).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The shortening of the dendritic arbor in class IV ddaC neurons observed in third instar larvae expressing Opa1Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4109(2)80 can be rescued by co-expression of PPP1R15Scer\UAS.cMa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Opa1Scer\UAS.T:Ivir\HA1
Opa1UAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (1)