Open Close
General Information
Symbol
Dmel\cic4
Species
D. melanogaster
Name
FlyBase ID
FBal0326590
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

12bp deletion that removes 4 amino acid residues (RQKL) from the cic C1 domain of cic.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

12bp deletion that removes 4 amino acid residues (RQKL) from the cic C1 domain, 3 of which are highly conserved residues from the C1 core.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

cic4/cic4 flies are semi-lethal and show a range of developmental defects. Surviving adults exhibit thickened wing veins and ectopic vein material in the wings. cic4/cic4 males are sterile and exhibit a severe genitalia rotation phenotype. Embryos produced by cic4/cic4 females lack all central thoracic and abdominal segmented regions.

cic4/cicQ474X and cic4/Df(3R)ED6027 adults exhibit wing defects including reduced wing size and ectopic wing vein material in the wings.

Embryos produced by cic1/cic4 females exhibit severe defects including loss of thoracic and abdominal regions.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (2)