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General Information
Symbol
Dmel\p53TM3
Species
D. melanogaster
Name
FlyBase ID
FBal0328062
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Inversion breakpoint (94D10 breakpoint of In(3LR)TM3a) within p53. The 5' end of this breakpoint corresponds to 3R:23050763 and the 3' end corresponds to 3R:23050764 (release 6 coordinates).

    Caused by aberration
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 1 )
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    γ-irradiated p53-ns/p53TM3 embryos and larval wing discs (the Tm3, Sb balancer has an inversion break point at the p53 gene) fail to show the expected increase in apoptosis.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressed by
    Statement
    Reference

    p53TM3/p53-ns has decreased cell death | larval stage | conditional phenotype, suppressible by Hsap\TP53WT.1

    p53TM3/p53-ns has decreased cell death | embryonic stage | conditional phenotype, suppressible by Hsap\TP53WT.1

    p53TM3/p53-ns has decreased cell death | larval stage | conditional phenotype, suppressible by Hsap\TP53WT.2

    p53TM3/p53-ns has decreased cell death | embryonic stage | conditional phenotype, suppressible by Hsap\TP53WT.2

    Phenotype Manifest In
    Suppressed by
    Statement
    Reference

    p53TM3/p53-ns has wing disc | larval stage | conditional phenotype, suppressible by Hsap\TP53WT.1

    p53TM3/p53-ns has wing disc | embryonic stage | conditional phenotype, suppressible by Hsap\TP53WT.1

    p53TM3/p53-ns has wing disc | larval stage | conditional phenotype, suppressible by Hsap\TP53WT.2

    p53TM3/p53-ns has wing disc | embryonic stage | conditional phenotype, suppressible by Hsap\TP53WT.2

    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    p53TM3
    Name Synonyms
    Secondary FlyBase IDs
      References (3)