FlyBase Allele Report: Dmel\PDZ-GEF[C1]

General Information

Symbol

Dmel\PDZ-GEF^C1

Species

D. melanogaster

Name

FlyBase ID

FBal0345052

Feature type

allele

Associated gene

Dmel\PDZ-GEF

Associated Insertion(s)

P{EP}PDZ-GEF^EP388

Carried in Construct

Also Known As

EP(2)388

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Boettner and Van Aelst, 2007)

Mutagen

ethyl methanesulfonate

(Boettner and Van Aelst, 2007)

Progenitor genotype

P{EP}PDZ-GEF^EP388

(Boettner and Van Aelst, 2007)

Associated Insertion(s)

P{EP}PDZ-GEF^EP388

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:6,323,797..6,323,797 [+]2L:6,323,660..6,323,660

(Boettner and Van Aelst, 2007)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

some die during embryonic stage (with PDZ-GEF^k13720)

(Boettner and Van Aelst, 2007)

Phenotype Manifest In

embryo (with PDZ-GEF^k13720)

(Boettner and Van Aelst, 2007)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

PDZ-GEF^C1/PDZ-GEF^k13720 has increased mortality during development phenotype, enhanceable by Rap1^B3/Rap1^CD3

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1/PDZ-GEF^k13720 has increased mortality during development phenotype, enhanceable by cno^mis1/cno²

(Boettner and Van Aelst, 2007)

Enhancer of

Statement

Reference

PDZ-GEF^C1/PDZ-GEF^k13720 is an enhancer of increased mortality during development phenotype of cno^mis1/cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1/PDZ-GEF^k13720 is an enhancer of abnormal cell migration | embryonic stage phenotype of cno^mis1/cno²

(Boettner and Van Aelst, 2007)

Other

Statement

Reference

PDZ-GEF^C1/PDZ-GEF^k13720, Rap1^B3/Rap1^CD3 has abnormal cell migration | embryonic stage phenotype

(Boettner and Van Aelst, 2007)

Phenotype Manifest In

Enhanced by

Statement

Reference

PDZ-GEF^C1/PDZ-GEF^k13720 has embryo phenotype, enhanceable by Rap1^B3/Rap1^CD3

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1/PDZ-GEF^k13720 has embryo phenotype, enhanceable by cno^mis1/cno²

(Boettner and Van Aelst, 2007)

Enhancer of

Statement

Reference

PDZ-GEF^C1/PDZ-GEF^k13720 is an enhancer of embryo phenotype of cno^mis1/cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1/PDZ-GEF^k13720 is an enhancer of embryonic/first instar larval cuticle | embryonic stage phenotype of cno^mis1/cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1/PDZ-GEF^k13720 is an enhancer of ectoderm | embryonic stage phenotype of cno^mis1/cno²

(Boettner and Van Aelst, 2007)

Other

Statement

Reference

PDZ-GEF^C1/PDZ-GEF^k13720, Rap1^B3/Rap1^CD3 has embryonic/first instar larval cuticle | embryonic stage phenotype

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1/PDZ-GEF^k13720, Rap1^B3/Rap1^CD3 has ectoderm | embryonic stage phenotype

(Boettner and Van Aelst, 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gef26^C1

(Boettner and Van Aelst, 2007)

PDZ-GEF^C1

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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