FlyBase Allele Report: Ecol\lexA[GAD.salm.EPv]

General Information

Symbol

Ecol\lexA^GAD.salm.EPv

Species

E. coli

Name

FlyBase ID

FBal0346744

Feature type

allele

Associated gene

Ecol\lexA

Associated Insertion(s)

Carried in Construct

P{salm-lexA::GAD.EPv}

Also Known As

sal^E/Pv-LHG

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Santabárbara-Ruiz et al., 2015)

Progenitor genotype

Carried in construct

P{salm-lexA::GAD.EPv}

Cytology

Description

Specific enhancer region of salm (EPv) controls expression of lexA::GAD.

(Santabárbara-Ruiz et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

salm

Encoded product / tool

lexA::GAD

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

wandering third instar larval stage

anterior-posterior compartment boundary of the wing disc | restricted | vicinity of

(Santabárbara-Ruiz et al., 2015)

wing pouch | restricted

(Santabárbara-Ruiz et al., 2015)

Additional Information

Statement

Reference

Ecol\lexA^GAD.salm.EPv drives expression in a wide central band in the wing pouch, centered on the anterior-posterior compartment boundary.

(Santabárbara-Ruiz et al., 2015)

Marker for

Reflects expression of

salm

(Santabárbara-Ruiz et al., 2015)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with lncRNA:CR40469^KO, rpr^lexAop.cSa

(Camilleri-Robles et al., 2024)

increased cell death | third instar larval stage, with rpr^lexAop.cSa

(Sun et al., 2020)

visible | adult stage, with lncRNA:CR40469^KO, rpr^lexAop.cSa

(Camilleri-Robles et al., 2024)

Phenotype Manifest In

wing, with lncRNA:CR40469^KO, rpr^lexAop.cSa

(Camilleri-Robles et al., 2024)

wing pouch | third instar larval stage, with rpr^lexAop.cSa

(Sun et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO, rpr^lexAop.cSa has visible | adult stage phenotype, suppressible | partially by Scer\GAL4^nub.PK/lncRNA:CR34335^UAS.cCa

(Camilleri-Robles et al., 2024)

NOT suppressed by

Statement

Reference

Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO, rpr^lexAop.cSa has decreased size | adult stage phenotype, non-suppressible by Scer\GAL4^nub.PK/lncRNA:CR34335^UAS.cCa

(Camilleri-Robles et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO, rpr^lexAop.cSa has wing phenotype, suppressible | partially by Scer\GAL4^nub.PK/lncRNA:CR34335^UAS.cCa

(Camilleri-Robles et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Ecol\lexA^GAD.salm.EPv

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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