FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\heca19
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General Information
Symbol
Dmel\heca19
Species
D. melanogaster
Name
FlyBase ID
FBal0346922
Feature type
allele
Associated gene
Dmel\heca
Associated Insertion(s)
P{GawB}heca19
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Varga et al., 2019)
Progenitor genotype
P{lacZ.ry+}hecaB5
(Varga et al., 2019)
Associated Insertion(s)
P{GawB}heca19
Cytology
Description

The P{lacZ.ry+} enhancer trap element in P{lacZ.ry+}hdcB5 has been replaced with a P{GawB} enhancer trap element by the simultaneous mobilization of P{lacZ.ry+}hdcB5 and a P{GawB} insertion. The P{GawB} element is located 8bp upstream of the original P{lacZ.ry+}hdcB5 insertion, being located 1025bp upstream of the hdc start codon.

(Varga et al., 2019)
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      hdc19 homozygotes exhibit precocious differentiation of lamellocytes and a significant reduction in the ratio of plasmatocytes within circulating hemocytes when compared to control third instar larvae.

      (Varga et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      heca19 is rescued by Scer\GAL4heca-19/hecaUAS.cSa

      (Varga et al., 2019)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hdc19
      heca19
      Name Synonyms
      Secondary FlyBase IDs
        References (1)