FlyBase Allele Report: Dmel\btl[RNAi.UAS.cUa]

General Information

Symbol

Dmel\btl^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0349907

Feature type

allele

Associated gene

Dmel\btl

Associated Insertion(s)

Carried in Construct

P{UAS-btl.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-btl.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of an RNAi line that targets btl.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

btl

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by N^RNAi.P.UAS, Ras85D^V12.UAS

(Tamamouna et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | larval stage, with Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

increased cell number | larval stage, with Scer\GAL4^Tep4.PU

(Destalminil-Letourneau et al., 2021)

Phenotype Manifest In

embryonic/larval crystal cell | increased number | larval stage, with Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

embryonic/larval crystal cell | increased number | larval stage, with Scer\GAL4^Tep4.PU

(Destalminil-Letourneau et al., 2021)

embryonic/larval plasmatocyte | increased number | larval stage, with Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^dome-PG125, btl^RNAi.UAS.cUa has increased cell number | larval stage phenotype, suppressible by htl^DN.UAS.cUa/Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

Enhancer of

Statement

Reference

btl^RNAi.UAS.cUa, Scer\GAL4^Tep4.PU is an enhancer of decreased cell number | larval stage phenotype of Itpr^UAS.cVa, Scer\GAL4^Tep4.PU

(Destalminil-Letourneau et al., 2021)

btl^RNAi.UAS.cUa, Scer\GAL4^dome-PG125 is an enhancer of decreased cell number | larval stage phenotype of CaMKII^UAS.cKa, Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

Suppressor of

Statement

Reference

Scer\GAL4^dome-PG125/btl^RNAi.UAS.cUa is a suppressor of increased cell number | larval stage phenotype of Scer\GAL4^dome-PG125, htl^DN.UAS.cUa

(Destalminil-Letourneau et al., 2021)

NOT Suppressor of

Statement

Reference

btl^RNAi.UAS.cUa, Scer\GAL4^esg.PU is a non-suppressor of increased occurrence of cell division | adult stage | progressive phenotype of SH3PX1^HMJ21552, Scer\GAL4^esg.PU

(Zhang et al., 2019)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^dome-PG125, btl^RNAi.UAS.cUa has embryonic/larval crystal cell | increased number | larval stage phenotype, suppressible by htl^DN.UAS.cUa/Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

Enhancer of

Statement

Reference

btl^RNAi.UAS.cUa, Scer\GAL4^Tep4.PU is an enhancer of embryonic/larval crystal cell | larval stage | decreased number phenotype of Itpr^UAS.cVa, Scer\GAL4^Tep4.PU

(Destalminil-Letourneau et al., 2021)

btl^RNAi.UAS.cUa, Scer\GAL4^dome-PG125 is an enhancer of embryonic/larval crystal cell | larval stage | decreased number phenotype of CaMKII^UAS.cKa, Scer\GAL4^dome-PG125

(Destalminil-Letourneau et al., 2021)

Suppressor of

Statement

Reference

Scer\GAL4^dome-PG125/btl^RNAi.UAS.cUa is a suppressor of embryonic/larval crystal cell | increased number | larval stage phenotype of Scer\GAL4^dome-PG125, htl^DN.UAS.cUa

(Destalminil-Letourneau et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

btl^RNAi.UAS.cUa is rescued by Scer\GAL4^dome-PG125/btl^λ.UAS

(Destalminil-Letourneau et al., 2021)

Rescues

Scer\GAL4^dome-PG125/btl^RNAi.UAS.cUa rescues btl^λ.UAS

(Destalminil-Letourneau et al., 2021)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

btl^RNAi.UAS.cUa

btl^RNAi

(Tamamouna et al., 2021)

btl^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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