FlyBase Allele Report: Dmel\btd[ΔBTD-box.4]

General Information

Symbol

Dmel\btd^ΔBTD-box.4

Species

D. melanogaster

Name

FlyBase ID

FBal0363182

Feature type

allele

Associated gene

Dmel\btd

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

loss of function allele

(Blom-Dahl et al., 2020)

Mutagen

CRISPR/Cas9

(Blom-Dahl et al., 2020)

Progenitor genotype

Cytology

Description

4aa deletion within the BTD-Box domain of btd.

(Blom-Dahl et al., 2020)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

X:9,696,022..9,696,033 [+]

Comment:

12bp (4aa) deletion within the BTD-Box domain of btd.

(Blom-Dahl et al., 2020)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

lethal - all die before end of P-stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

viable

(Blom-Dahl et al., 2020)

visible | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

Phenotype Manifest In

leg | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

segment of leg | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Df(1)btd-Sp1/btd^ΔBTD-box.4 has decreased size | adult stage phenotype, enhanceable by Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

Df(1)btd-Sp1/btd^ΔBTD-box.4 has visible | adult stage phenotype, enhanceable by Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

NOT Enhancer of

Statement

Reference

btd^ΔBTD-box.4 is a non-enhancer of decreased size | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

btd^ΔBTD-box.4 is a non-enhancer of visible | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

NOT Suppressor of

Statement

Reference

btd^ΔBTD-box.4 is a non-suppressor of decreased size | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

btd^ΔBTD-box.4 is a non-suppressor of visible | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

Other

Statement

Reference

Sp1^ΔBTD-box, btd^ΔBTD-box.4 has partially lethal phenotype

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box/Df(1)btd-Sp1, btd^ΔBTD-box.4 has lethal - all die before end of P-stage phenotype

(Blom-Dahl et al., 2020)

Phenotype Manifest In

Enhanced by

Statement

Reference

Df(1)btd-Sp1/btd^ΔBTD-box.4 has leg | adult stage phenotype, enhanceable by Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

Df(1)btd-Sp1/btd^ΔBTD-box.4 has segment of leg | adult stage phenotype, enhanceable by Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

NOT Enhancer of

Statement

Reference

btd^ΔBTD-box.4 is a non-enhancer of leg | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

btd^ΔBTD-box.4 is a non-enhancer of segment of leg | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

NOT Suppressor of

Statement

Reference

btd^ΔBTD-box.4 is a non-suppressor of leg | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

btd^ΔBTD-box.4 is a non-suppressor of segment of leg | adult stage phenotype of Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

btd^ΔBTD-box.4

btd^ΔBTD-box

(Blom-Dahl et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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