FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tdc2B3RT
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General Information
Symbol
Dmel\Tdc2B3RT
Species
D. melanogaster
Name
FlyBase ID
FBal0363913
Feature type
allele
Associated gene
Dmel\Tdc2
Associated Insertion(s)
TI{lexA::UnkAD}Tdc2B3RT
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(McKinney et al., 2020)
Mutagen
gene targeting by homologous recombination
(McKinney et al., 2020)
CRISPR/Cas9
(McKinney et al., 2020)
Progenitor genotype
Associated Insertion(s)
TI{lexA::UnkAD}Tdc2B3RT
Cytology
Description

Two B3RT sites have been inserted into the endogenous Tdc2 locus, along with sequence encoding a lexA::UnkAD driver downstream of the 3' B3RT site. In the presence of B3R recombinase Tdc2 coding exons are excised, resulting in the lexA::UnkAD driver being expressed under the control of endogenous Tdc2 regulatory sequences. Tdc2 function is affected before and after excision.

(McKinney et al., 2020)
Allele components
Component
Use(s)
Inserted element
TI{lexA::UnkAD}
Encoded product / tool
lexA::UnkAD
Also carries
B3RT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Tdc2B3RT
      Name Synonyms
      Secondary FlyBase IDs
        References (2)