FlyBase Allele Report: Dmel\Tnpo[Δ11]

General Information

Symbol

Dmel\Tnpo^Δ11

Species

D. melanogaster

Name

FlyBase ID

FBal0369503

Feature type

allele

Associated gene

Dmel\Tnpo

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Goodman et al., 2021)

Mutagen

P-element activity

(Goodman et al., 2021)

Progenitor genotype

P{GawB}NP4408

(Goodman et al., 2021)

Cytology

Description

Imprecise excision of the P{GawB}NP4408 insertion.

(Goodman et al., 2021)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies

CEC

(Goodman et al., 2021)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

cell lethal | adult stage | somatic clone - tissue specific

(Goodman et al., 2021)

lethal - all die before end of larval stage (with Tnpo^{CR92235-TG4.2})

(Goodman et al., 2021)

lethal - all die before end of larval stage (with Tnpo^G736D)

(Goodman et al., 2021)

lethal - all die before end of second instar larval stage

(Goodman et al., 2021)

lethal - all die before end of second instar larval stage (with Df(3L)Exel8101)

(Goodman et al., 2021)

Phenotype Manifest In

eye | somatic clone - tissue specific

(Goodman et al., 2021)

Detailed Description

Statement

Reference

Tnpo^Δ11 is cell lethal in the eye, as no ey-FLP-induced clones can be found.

(Goodman et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Tnpo^Δ11 is rescued by Tnpo^GR

(Goodman et al., 2021)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Tnpo^Δ11

dTnpo^Δ11

(Goodman et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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