FlyBase Allele Report: Dmel\5-HT1B[RNAi.UAS.cUa]

General Information

Symbol

Dmel\5-HT1B^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0369523

Feature type

allele

Associated gene

Dmel\5-HT1B

Associated Insertion(s)

Carried in Construct

P{UAS-5-HT1B.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-5-HT1B.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of a 5-HT1B RNAi construct.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

5-HT1B

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response | larval stage, with Scer\GAL4^GMR64A03

(Liu et al., 2025)

abnormal immune response | larval stage, with Scer\GAL4^Hand.Δ

(Liu et al., 2025)

Phenotype Manifest In

embryonic/larval lymph gland | larval stage, with Scer\GAL4^Hand.Δ

(Liu et al., 2025)

extracellular matrix | larval stage | conditional, with Scer\GAL4^Hand.Δ

(Liu et al., 2025)

lamellocyte | decreased number, with Scer\GAL4^Hand.Δ

(Liu et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

5-HT1B^RNAi.UAS.cUa, Scer\GAL4^Hand.Δ has abnormal immune response | larval stage phenotype, suppressible | partially by hop^Tum.UAS, Scer\GAL4^Hand.Δ

(Liu et al., 2025)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

5-HT1B^RNAi.UAS.cUa, Scer\GAL4^Hand.Δ has extracellular matrix | larval stage | conditional phenotype, non-enhanceable by Timp^UAS.cPa, Scer\GAL4^Hand.Δ

(Liu et al., 2025)

Suppressed by

Statement

Reference

5-HT1B^RNAi.UAS.cUa, Scer\GAL4^Hand.Δ has embryonic/larval lymph gland | larval stage phenotype, suppressible | partially by Timp^UAS.cPa, Scer\GAL4^Hand.Δ

(Liu et al., 2025)

5-HT1B^RNAi.UAS.cUa, Scer\GAL4^Hand.Δ has embryonic/larval lymph gland | larval stage phenotype, suppressible | partially by hop^Tum.UAS, Scer\GAL4^Hand.Δ

(Liu et al., 2025)

5-HT1B^RNAi.UAS.cUa, Scer\GAL4^Hand.Δ has extracellular matrix | larval stage | conditional phenotype, suppressible | partially by hop^Tum.UAS, Scer\GAL4^Hand.Δ

(Liu et al., 2025)

NOT suppressed by

Statement

Reference

5-HT1B^RNAi.UAS.cUa, Scer\GAL4^Hand.Δ has extracellular matrix | larval stage | conditional phenotype, non-suppressible by Timp^UAS.cPa, Scer\GAL4^Hand.Δ

(Liu et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

5-HT1B^RNAi.UAS.cUa

5-HT1B^TRiP.cUa

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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