FlyBase Allele Report: Dmel\Gat[33-1]

General Information

Symbol

Dmel\Gat^33-1

Species

D. melanogaster

Name

FlyBase ID

FBal0375952

Feature type

allele

Associated gene

Dmel\Gat

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - molecular evidence

Mutagen

TALEN

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Chaturvedi et al., 2022)

Mutagen

TALEN

(Chaturvedi et al., 2022)

Progenitor genotype

Cytology

Description

7 nucleotide deletion within endogenous Gat results in a frameshift and early termination; low levels of N-terminally truncated Gat are produced.

(Chaturvedi et al., 2022)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

4:629,851..629,857 [+]

Comment:

A 7bp deletion starting in codon 6 of Gat leads to a frameshift and early translation termination.

(Chaturvedi et al., 2022)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage

(Chaturvedi et al., 2022)

abnormal sleep | adult stage

(Chaturvedi et al., 2022)

increased sleep | adult stage

(Chaturvedi et al., 2022)

lethal (with Df(4)Gat^Δ64kb)

(Chaturvedi et al., 2022)

viable

(Chaturvedi et al., 2022)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Gat^33-1 is a non-enhancer of decreased sleep | adult stage phenotype of Rdl^GD4609, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of abnormal sleep | adult stage phenotype of Rdl^GD4609, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of decreased sleep | adult stage phenotype of Nlg4^GD3083, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of abnormal sleep | adult stage phenotype of Nlg4^GD3083, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of decreased sleep | adult stage phenotype of wake^D2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of abnormal sleep | adult stage phenotype of wake^D2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of decreased sleep | adult stage phenotype of Scer\GAL4^P2.4.Pdf, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of abnormal sleep | adult stage phenotype of Scer\GAL4^P2.4.Pdf, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of decreased sleep | adult stage phenotype of Scer\GAL4^dimm-929, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-enhancer of abnormal sleep | adult stage phenotype of Scer\GAL4^dimm-929, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

NOT Suppressor of

Statement

Reference

Gat^33-1 is a non-suppressor of decreased sleep | adult stage phenotype of Rdl^GD4609, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of abnormal sleep | adult stage phenotype of Rdl^GD4609, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of decreased sleep | adult stage phenotype of Nlg4^GD3083, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of abnormal sleep | adult stage phenotype of Nlg4^GD3083, Scer\GAL4^P2.4.Pdf

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of decreased sleep | adult stage phenotype of wake^D2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of abnormal sleep | adult stage phenotype of wake^D2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of decreased sleep | adult stage phenotype of Scer\GAL4^P2.4.Pdf, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of abnormal sleep | adult stage phenotype of Scer\GAL4^P2.4.Pdf, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of decreased sleep | adult stage phenotype of Scer\GAL4^dimm-929, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Gat^33-1 is a non-suppressor of abnormal sleep | adult stage phenotype of Scer\GAL4^dimm-929, wake^RNAi.UAS.2

(Chaturvedi et al., 2022)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

Gat^33-1 is partially rescued by Gat^+tCH322-1B12

(Chaturvedi et al., 2022)

Gat^33-1 is partially rescued by Gat^UAS.cSa/Scer\GAL4^alrm.PD

(Chaturvedi et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gat^33-1

gat^33-1

(Chaturvedi et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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