FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\eIF4E5B8b
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General Information
Symbol
Dmel\eIF4E5B8b
Species
D. melanogaster
Name
FlyBase ID
FBal0389272
Feature type
allele
Associated gene
Dmel\eIF4E5
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Shao et al., 2023)
Mutagen
CRISPR/Cas9
(Shao et al., 2023)
Progenitor genotype
Cytology
Description

3bp deletion in eIF4E5.

(Shao et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:7,895,202..7,895,204 [+]
Comment:

A 3bp deletion that removes amino acid 55 of eIF4E5.

(Shao et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      eIF4E5B8b has spermatid cyst phenotype, enhanceable by aPKCk06403

      (Shao et al., 2023)

      eIF4E5B8b has spermatid cyst phenotype, enhanceable by orb236

      (Shao et al., 2023)
      Enhancer of
      Statement
      Reference

      eIF4E5B8b is an enhancer of spermatid cyst phenotype of aPKCk06403

      (Shao et al., 2023)

      eIF4E5B8b is an enhancer of spermatid cyst phenotype of orb236

      (Shao et al., 2023)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      eIF4E5B8b is rescued by eIF4E53xTag:FLAG

      (Shao et al., 2023)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      eIF4E-5B8b
      (Shao et al., 2023)
      eIF4E5B8b
      Name Synonyms
      Secondary FlyBase IDs
        References (1)