FlyBase Allele Report: Dmel\Cyp6g2[KO]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Cyp6g2^KO

General Information

Symbol

Dmel\Cyp6g2^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0402388

Feature type

allele

Associated gene

Associated Insertion(s)

TI{TI}Cyp6g2^KO

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Jia et al., 2024)

Mutagen

(Jia et al., 2024)

Progenitor genotype

Associated Insertion(s)

TI{TI}Cyp6g2^KO

Cytology

Description

A 180-bp deletion and a 22-bp nucleotide insertion in Cyp6g2.

(Jia et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body size | P-stage

(Jia et al., 2024)

decreased fecundity

(Jia et al., 2024)

decreased size | oogenesis

(Jia et al., 2024)

partially lethal - majority die

(Jia et al., 2024)

some die during embryonic stage

(Jia et al., 2024)

some die during larval stage

(Jia et al., 2024)

some die during P-stage

(Jia et al., 2024)

Phenotype Manifest In

(Jia et al., 2024)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Cyp6g2^KO, jhamt² has abnormal developmental rate phenotype

(Jia et al., 2024)

Cyp6g2^KO, jhamt² has decreased body size | P-stage phenotype

(Jia et al., 2024)

Cyp6g2^KO, jhamt² has lethal - all die before end of P-stage phenotype

(Jia et al., 2024)

Cyp6g2^KO, jhamt² has majority die during P-stage phenotype

(Jia et al., 2024)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Cyp6g2^KO

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections