FlyBase Allele Report: Dmel\dgt6[19A]

General Information

Symbol

Dmel\dgt6^19A

Species

D. melanogaster

Name

FlyBase ID

FBal0403133

Feature type

allele

Associated gene

Dmel\dgt6

Associated Insertion(s)

P{?GSV6}dgt6^19A

Carried in Construct

Key Links

Allele class

hypomorphic allele - molecular evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Zhang et al., 2024)

Mutagen

Delta2-3 transposase

(Zhang et al., 2024)

Progenitor genotype

P{GSV6}dgt6^GS11802

(Zhang et al., 2024)

Associated Insertion(s)

P{?GSV6}dgt6^19A

Cytology

Description

Imprecise excision of the P{GSV6}dgt6^GS11802 insertion. The dgt6 coding sequence has not been affected by the excision, but the UAS binding sites originally present in the inserted P{GSV6} element have been removed.

(Zhang et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage | somatic clone

(Zhang et al., 2024)

Phenotype Manifest In

dendrite terminus | decreased number | larval stage | somatic clone

(Zhang et al., 2024)

dendritic tree | larval stage

(Zhang et al., 2024)

larval multidendritic class IV neuron | somatic clone

(Zhang et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

γTub23C^A15-2, dgt6^19A has abnormal neuroanatomy | larval stage phenotype

(Zhang et al., 2024)

Grip71¹²⁰, dgt6^19A has abnormal neuroanatomy | larval stage phenotype

(Zhang et al., 2024)

Phenotype Manifest In

Other

Statement

Reference

γTub23C^A15-2, dgt6^19A has larval multidendritic class IV neuron phenotype

(Zhang et al., 2024)

γTub23C^A15-2, dgt6^19A has dendritic tree | larval stage phenotype

(Zhang et al., 2024)

γTub23C^A15-2, dgt6^19A has dendrite terminus | larval stage | decreased number phenotype

(Zhang et al., 2024)

Grip71¹²⁰, dgt6^19A has larval multidendritic class IV neuron phenotype

(Zhang et al., 2024)

Grip71¹²⁰, dgt6^19A has dendritic tree | larval stage phenotype

(Zhang et al., 2024)

Grip71¹²⁰, dgt6^19A has dendrite terminus | larval stage | decreased number phenotype

(Zhang et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

dgt6^19A is rescued by dgt6^UAS.cZa/Scer\GAL4^elav.PU

(Zhang et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

dgt6^19A

(Zhang et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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