FlyBase Allele Report: Dmel\upd3[RNAi.UAS.cUa]

General Information

Symbol

Dmel\upd3^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0407721

Feature type

allele

Associated gene

Dmel\upd3

Associated Insertion(s)

Carried in Construct

P{UAS-upd3.RNAi.U}

Also Known As

UAS-Upd3^RNAi

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-upd3.RNAi.U}

Cytology

Description

UAS sequences regulate expression of an RNAi line that targets upd3.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

upd3

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

DOES NOT ameliorate cancer

modeled by Hipk^UAS.Tag:HA

(Blaquiere et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

upd3^RNAi.UAS.cUa, Scer\GAL4^dpp.blk1 is an enhancer of neoplasia phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

NOT Suppressor of

Statement

Reference

upd3^RNAi.UAS.cUa, Scer\GAL4^dpp.blk1 is a non-suppressor of abnormal cell migration | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Other

Statement

Reference

Acbp6^KK111610, Scer\GAL4^NP0001, upd3^RNAi.UAS.cUa has decreased cell number | adult stage | conditional phenotype

(Li and Karpac, 2023)

Acbp6^KK111610, Scer\GAL4^NP0001, upd3^RNAi.UAS.cUa has decreased occurrence of cell division | adult stage | conditional phenotype

(Li and Karpac, 2023)

Phenotype Manifest In

Enhancer of

Statement

Reference

upd3^RNAi.UAS.cUa, Scer\GAL4^dpp.blk1 is an enhancer of wing disc phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Other

Statement

Reference

Acbp6^KK111610, Scer\GAL4^NP0001, upd3^RNAi.UAS.cUa has adult midgut | conditional phenotype

(Li and Karpac, 2023)

Acbp6^KK111610, Scer\GAL4^NP0001, upd3^RNAi.UAS.cUa has intestinal stem cell | decreased number | conditional phenotype

(Li and Karpac, 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

upd3^RNAi.UAS.cUa

upd3^VDRC.cUa

Name Synonyms

Secondary FlyBase IDs

FBal0397459
FBal0351532

References (3)

Report Sections

Open Close