FB2026_03 , released September 17, 2026
Split System Combination: Scer\GAL4DBD.R71D01∩Hsap\RELAAD.R18C11
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General Information
Symbol
Scer\GAL4DBD.R71D01∩Hsap\RELAAD.R18C11
FlyBase ID
FBco0001722
Feature Type
split system combination
Component Alleles
Combination components
Component allele Hsap\RELAAD.R18C11
Component
Use(s)
Regulatory region(s)
GMR18C11
Encoded product / tool
p65(AD)::Zip+
Description

The GMR18C11 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the p65(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the p65 activation domain).

(Rubin Laboratory at Janelia Farm, 2017)
Component allele Scer\GAL4DBD.R71D01
Component
Use(s)
Regulatory region(s)
GMR71D01
Encoded product / tool
GAL4(DBD)::Zip-
Description

The GMR71D01 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain).

(Rubin Laboratory at Janelia Farm, 2017)
Expression Data
Reporters Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
antennal grooming descending neuron 1
(Hampel et al., 2015)
Additional Information
Statement
Reference

In a split-GAL4 system, HsapRELAAD.R18C11 drives expression in antennal grooming descending neuron 1 when combined with ScerGAL4DBD.R71D01. These neurons were seen in close proximity to EcollexAGMR26B12 expressing antennal grooming brain interneuron 2 and EcollexAGMR27H08 expressing zone C/E Johnston organ neurons. Positive GRASP (GFP reconstitution across synaptic partners) signals were seen between C/E Johnston organ neurons and antennal grooming descending neuron 1 using these drivers.

(Hampel et al., 2015)

In a split-GAL4 system, ScerGAL4DBD.R71D01 drives expression in antennal grooming descending neuron 1 when combined with HsapRELAAD.R18C11, in antennal grooming brain interneuron 1 and the adult central complex when combined with HsapRELAAD.R11B11, and in antennal grooming descending neuron 1, antennal grooming brain interneuron 1, the optic lobe and thoracico-abdominal ganglion when combined with HsapRELAAD.R34C03. Antennal grooming descending neuron 1 neurons were seen in close proximity to EcollexAGMR26B12 expressing antennal grooming brain interneuron 2 and EcollexAGMR27H08 expressing zone C/E Johnston organ neurons. Positive GRASP (GFP reconstitution across synaptic partners) signals were seen between C/E Johnston organ neurons and antennal grooming descending neuron 1 using these drivers.

(Hampel et al., 2015)
Marker for
Stocks (0)
External Crossreferences and Linkouts ( 0 )
References (1)