Please see the JBrowse view of Dmel\Sap47 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Gene model reviewed during 5.43
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.53
Stop-codon suppression (UAA) postulated; FBrf0234051.
Gene model reviewed during 6.25
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sap47 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Sap47 protein is strongly expressed in the neuropil regions of the larval brain. It is expressed in restricted regions of the taste organs of the larval head, including the dorsal (DO) and terminal (TO) organs, the pharyngeal sense organs (DPS or epiphysis; PPS or hypopharyngeal; VPS or hypophysis) and in the larval visual organ (Bolwig organ). Sap47 is also found in the presynaptic terminals at the neuromuscular junction, closely associated with the synaptic vesicles.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Sap47 in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
monoclonal
Sap47 functions in associative behavioral and short-term synaptic plasticity, but does not contribute to basic synaptic transmission or to task-relevant sensory-motor function.
Identification: identified as an antigen recognised by the MAB nc46 antibody.
Encodes a protein that is expressed in most but not all synaptic terminals of the nervous system.