Gene model reviewed during 5.45
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Phosphorylated by aPKC which lowers lipid affinity and promotes dissociation from the cell cortex (PubMed:26481050, PubMed:32579558). In the photoreceptor cells, aPKC-mediated phosphorylation leads to its displacement from the stalk apical cortex and thus restricts its localization to the rhabdomeric apical cortex where it functions (PubMed:32579558). Dephosphorylation appears to be light-dependent (PubMed:9697866).
The phospho-regulated basic and hydrophobic (PRBH) motif is sufficient and important for interaction with phospholipids permitting cortical localization (PubMed:26481050). Phosphorylation of the PRBH motif by aPKC inhibits the association of the protein with the cortical membrane (PubMed:26481050, PubMed:32579558).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PIP82 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\PIP82 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.