FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Ugt35B1
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General Information
Symbol
Dmel\Ugt35B1
Species
D. melanogaster
Name
UDP-glycosyltransferase family 35 member B1
Annotation Symbol
CG6649
Feature Type
protein_coding_gene
FlyBase ID
FBgn0026314
Gene Model Status
Current
Stock Availability
8 publicly available
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

Ugt35b, UDP-glycosyltransferase 35b

Key Links
Genomic Location
Cytogenetic map
86D5-86D5
Sequence location
Recombination map
3-50
RefSeq locus
NT_033777 REGION:11168503..11170246
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (5 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables UDP-glycosyltransferase activity
inferred from mutant phenotype
(Pfannenstiel et al., 2026)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables UDP-glycosyltransferase activity
inferred from sequence model
(Ahn and Marygold, 2021)
inferred from electronic annotation with InterPro:IPR002213
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN005360456
(GO Reference Genome Project, 2011-)
inferred from sequence or structural similarity with UniProtKB:P54855
(Gene Ontology Curators, 2002-)
Biological Process (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in detoxification of nitrogen compound
inferred from mutant phenotype
(Pfannenstiel et al., 2026)
involved_in response to nicotine
inferred from mutant phenotype
(Pfannenstiel et al., 2026)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in endoplasmic reticulum membrane
inferred from sequence model
(Ahn and Marygold, 2021)
located_in membrane
inferred from sequence model
(Wang et al., 1999)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES -
The GT1 family of UDP-glycosyltransferases (UGTs) catalyze the transfer the glycosyl group from a nucleotide sugar, such as UDP-glucuronic acid, UDP-galactose, UDP-glucose or UDP-xylose, to a variety of small hydrophobic acceptor molecules (aglycones), resulting in more hydrophilic compounds that are efficiently excreted. Mammalian/vertebrate UGTs mainly use UDP-glucuronic acid as the sugar donor, whereas invertebrates and plants appear to use UDP-glucose as the main donor. Insect UGTs play a major role in the detoxification of substrates, cuticle formation, pigmentation and olfaction. The GT1 family is defined by a common protein structure and signature sequence of 44 amino acids responsible for binding the UDP moiety of the sugar donor. (Adapted from FBrf0152079 and PMID:26453144).
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Ugt35B1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VGT0)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Ugt35B1-RA
FBtr0082375
NM_079589
1672
516
Additional Transcript Data and Comments
Reported size (kB)

1.704 (longest cDNA)

(Wang et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Ugt35B1-PA
FBpp0081851
58.3
516
9.32
Q9VGT0
NP_524313
AAF54595
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

516 (aa)

(Wang et al., 1999)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ugt35B1 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.04

Transcript Expression
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
(Wang et al., 1999)
adult head
(Wang et al., 1999)
leg
(Wang et al., 1999)
third segment of antenna
(Wang et al., 1999)
Additional Descriptive Data

Ugt35B1 transcript is expressed in appendages, at much higher levels in antennal segment 3 than in legs. Expression is also detected at low levels in heads and bodies.

(Wang et al., 1999)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Ugt35B1 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 0 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Ugt35B1
Transgenic constructs containing regulatory region of Ugt35B1
Aberrations (Deficiencies and Duplications) ( 1 )
Inferred from experimentation ( 1 )
Gene disrupted in
Df(3R)Exel8152
(Ryder, 2004.4.26)
Inferred from location ( 8 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (22)
Hsap\UGT2A3
11 of 14
Yes
Yes
Hsap\UGT1A1
10 of 14
No
Yes
Hsap\UGT1A4
10 of 14
No
Yes
Hsap\UGT1A6
10 of 14
No
Yes
Hsap\UGT1A7
10 of 14
No
Yes
Hsap\UGT1A8
10 of 14
No
Yes
Hsap\UGT1A9
10 of 14
No
Yes
Hsap\UGT1A10
10 of 14
No
Yes
Hsap\UGT2A1
10 of 14
No
Yes
Hsap\UGT2B4
10 of 14
No
Yes
Hsap\UGT2B7
10 of 14
No
Yes
Hsap\UGT2B10
10 of 14
No
Yes
Hsap\UGT2B11
10 of 14
No
No
Hsap\UGT2B15
10 of 14
No
Yes
Hsap\UGT2B17
10 of 14
No
Yes
Hsap\UGT2B28
10 of 14
No
Yes
Hsap\UGT1A3
9 of 14
No
Yes
Hsap\UGT1A5
9 of 14
No
Yes
Hsap\UGT2A2
9 of 14
No
Yes
Hsap\UGT8
8 of 14
No
Yes
Hsap\UGT3A1
5 of 14
No
Yes
Hsap\UGT3A2
5 of 14
No
Yes
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (19)
Rnor\RGD1559459
10 of 14
Yes
No
Rnor\Ugt2a3
10 of 14
Yes
Yes
Rnor\Ugt2b15
10 of 14
Yes
Yes
Rnor\Ugt2b35
10 of 14
Yes
Yes
Rnor\Ugt1a1
9 of 14
No
No
Rnor\Ugt1a5
9 of 14
No
Yes
Rnor\Ugt2b17
9 of 14
No
Yes
Rnor\Ugt2b37
9 of 14
No
Yes
Rnor\Ugt1a2
8 of 14
No
Yes
Rnor\Ugt1a3
8 of 14
No
Yes
Rnor\Ugt1a6
8 of 14
No
Yes
Rnor\Ugt1a7c
8 of 14
No
No
Rnor\Ugt1a8
8 of 14
No
Yes
Rnor\Ugt2a1
8 of 14
No
Yes
Rnor\Ugt2b7
8 of 14
No
Yes
Rnor\Ugt2b
8 of 14
No
Yes
Rnor\Ugt8
8 of 14
No
Yes
Rnor\Ugt3a2
4 of 14
No
No
Rnor\Ugt2b10
2 of 14
No
Yes
Mus musculus (laboratory mouse) (22)
Mmus\Ugt2a3
11 of 14
Yes
Yes
Mmus\Ugt1a1
10 of 14
No
Yes
Mmus\Ugt1a2
10 of 14
No
Yes
Mmus\Ugt1a5
10 of 14
No
Yes
Mmus\Ugt1a6a
10 of 14
No
Yes
Mmus\Ugt1a6b
10 of 14
No
Yes
Mmus\Ugt1a7c
10 of 14
No
No
Mmus\Ugt1a8
10 of 14
No
Yes
Mmus\Ugt1a9
10 of 14
No
Yes
Mmus\Ugt2a1
10 of 14
No
Yes
Mmus\Ugt2b1
10 of 14
No
Yes
Mmus\Ugt2b5
10 of 14
No
Yes
Mmus\Ugt2b34
10 of 14
No
Yes
Mmus\Ugt2b35
10 of 14
No
Yes
Mmus\Ugt2b36
10 of 14
No
Yes
Mmus\Ugt2b37
10 of 14
No
Yes
Mmus\Ugt2b38
10 of 14
No
Yes
Mmus\Ugt2a2
9 of 14
No
Yes
Mmus\Ugt8a
9 of 14
No
Yes
Mmus\Ugt3a1
5 of 14
No
Yes
Mmus\Ugt3a2
5 of 14
No
Yes
Mmus\Ugt1a10
3 of 14
No
Yes
Xenopus tropicalis (Western clawed frog) (15)
Xtro\ugt1a1
7 of 13
Yes
No
Xtro\ugt1a6
7 of 13
Yes
No
Xtro\ugt2a1
6 of 13
No
Yes
Xtro\ugt8
4 of 13
No
No
Xtro\capsl
3 of 13
No
No
Xtro\arhgap17
1 of 13
No
No
Xtro\eif2b3
1 of 13
No
No
Xtro\fdx2
1 of 13
No
No
Xtro\galnt10
1 of 13
No
No
Xtro\grik3
1 of 13
No
No
Xtro\LOC100488176
1 of 13
No
No
Xtro\LOC100490653
1 of 13
No
Yes
Xtro\LOC100493420
1 of 13
No
No
Xtro\rps15
1 of 13
No
No
Xtro\XB5897453
1 of 13
No
Yes
Danio rerio (Zebrafish) (36)
Drer\ugt2a5
11 of 14
Yes
Yes
Drer\ugt2b3
11 of 14
Yes
Yes
Drer\ugt5a1
10 of 14
No
Yes
Drer\ugt5a2
10 of 14
No
Yes
Drer\ugt5c1
10 of 14
No
Yes
Drer\ugt5c2
10 of 14
No
Yes
Drer\ugt5c3
10 of 14
No
Yes
Drer\ugt5d1
10 of 14
No
Yes
Drer\ugt5g2
10 of 14
No
Yes
Drer\ugt1ab
9 of 14
No
No
Drer\ugt2a2
9 of 14
No
Yes
Drer\ugt2a4
9 of 14
No
Yes
Drer\ugt5b2
9 of 14
No
Yes
Drer\ugt5b3
9 of 14
No
Yes
Drer\ugt5b4
9 of 14
No
Yes
Drer\ugt5e1
9 of 14
No
Yes
Drer\ugt5g1
9 of 14
No
Yes
Drer\ugt1a7
8 of 14
No
No
Drer\ugt2b5
8 of 14
No
Yes
Drer\ugt5f1
8 of 14
No
Yes
Drer\ugt8
8 of 14
No
Yes
Drer\ugt2a1
3 of 14
No
Yes
Drer\ugt2a3
3 of 14
No
Yes
Drer\ugt2a6
3 of 14
No
Yes
Drer\ugt1b1
2 of 14
No
Yes
Drer\ugt1b2
2 of 14
No
Yes
Drer\ugt1b3
2 of 14
No
Yes
Drer\ugt1b4
2 of 14
No
Yes
Drer\ugt1b7
2 of 14
No
Yes
Drer\ugt2b6
2 of 14
No
Yes
Drer\ugt5b5
2 of 14
No
Yes
Drer\LOC571561
1 of 14
No
Yes
Drer\ugt1a4
1 of 14
No
Yes
Drer\ugt1b5
1 of 14
No
Yes
Drer\ugt2b1
1 of 14
No
Yes
Drer\ugt5b1
1 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (71)
Cele\ugt-58
7 of 14
Yes
Yes
Cele\ugt-20
6 of 14
No
No
Cele\ugt-22
6 of 14
No
No
Cele\ugt-26
6 of 14
No
No
Cele\ugt-33
6 of 14
No
No
Cele\ugt-49
6 of 14
No
No
Cele\ugt-53
6 of 14
No
Yes
Cele\ugt-61
6 of 14
No
No
Cele\ugt-62
6 of 14
No
No
Cele\F10D2.8
5 of 14
No
No
Cele\H23N18.4
5 of 14
No
No
Cele\ugt-1
5 of 14
No
No
Cele\ugt-2
5 of 14
No
No
Cele\ugt-3
5 of 14
No
No
Cele\ugt-4
5 of 14
No
No
Cele\ugt-5
5 of 14
No
No
Cele\ugt-6
5 of 14
No
No
Cele\ugt-7
5 of 14
No
No
Cele\ugt-8
5 of 14
No
No
Cele\ugt-9
5 of 14
No
No
Cele\ugt-10
5 of 14
No
No
Cele\ugt-11
5 of 14
No
No
Cele\ugt-12
5 of 14
No
No
Cele\ugt-13
5 of 14
No
No
Cele\ugt-14
5 of 14
No
No
Cele\ugt-15
5 of 14
No
No
Cele\ugt-16
5 of 14
No
No
Cele\ugt-17
5 of 14
No
No
Cele\ugt-18
5 of 14
No
No
Cele\ugt-19
5 of 14
No
No
Cele\ugt-23
5 of 14
No
No
Cele\ugt-24
5 of 14
No
No
Cele\ugt-25
5 of 14
No
No
Cele\ugt-27
5 of 14
No
No
Cele\ugt-28
5 of 14
No
No
Cele\ugt-29
5 of 14
No
No
Cele\ugt-30
5 of 14
No
No
Cele\ugt-31
5 of 14
No
No
Cele\ugt-32
5 of 14
No
No
Cele\ugt-34
5 of 14
No
No
Cele\ugt-35
5 of 14
No
No
Cele\ugt-36
5 of 14
No
No
Cele\ugt-37
5 of 14
No
No
Cele\ugt-38
5 of 14
No
No
Cele\ugt-39
5 of 14
No
No
Cele\ugt-40
5 of 14
No
No
Cele\ugt-41
5 of 14
No
No
Cele\ugt-42
5 of 14
No
No
Cele\ugt-44
5 of 14
No
No
Cele\ugt-45
5 of 14
No
No
Cele\ugt-47
5 of 14
No
No
Cele\ugt-48
5 of 14
No
No
Cele\ugt-50
5 of 14
No
No
Cele\ugt-59
5 of 14
No
No
Cele\ugt-66
5 of 14
No
No
Cele\C03A7.13
4 of 14
No
No
Cele\ugt-21
4 of 14
No
No
Cele\ugt-43
4 of 14
No
No
Cele\ugt-46
4 of 14
No
No
Cele\ugt-51
4 of 14
No
No
Cele\ugt-52
4 of 14
No
No
Cele\ugt-54
4 of 14
No
Yes
Cele\ugt-55
4 of 14
No
No
Cele\ugt-56
4 of 14
No
No
Cele\ugt-60
4 of 14
No
No
Cele\ugt-57
3 of 14
No
No
Cele\ugt-63
3 of 14
No
No
Cele\ugt-64
3 of 14
No
No
Cele\ugt-65
3 of 14
No
No
Cele\T19H12.12
2 of 14
No
No
Cele\Y43D4A.2
2 of 14
No
No
Anopheles gambiae (African malaria mosquito) (24)
Agam\AgaP_AGAP006222
7 of 12
Yes
No
Agam\AgaP_AGAP006223
7 of 12
Yes
No
Agam\AgaP_AGAP007029
7 of 12
Yes
No
Agam\AgaP_AGAP006775
6 of 12
No
Yes
Agam\AgaP_AGAP007028
6 of 12
No
No
Agam\AgaP_AGAP007588
6 of 12
No
No
Agam\AgaP_AGAP007589
6 of 12
No
No
Agam\AgaP_AGAP011564
6 of 12
No
No
Agam\AgaP_AGAP002783
5 of 12
No
No
Agam\AgaP_AGAP005163
5 of 12
No
No
Agam\AgaP_AGAP005750
5 of 12
No
Yes
Agam\AgaP_AGAP005751
5 of 12
No
Yes
Agam\AgaP_AGAP005753
5 of 12
No
Yes
Agam\AgaP_AGAP005754
5 of 12
No
Yes
Agam\AgaP_AGAP007374
5 of 12
No
No
Agam\AgaP_AGAP007990
5 of 12
No
No
Agam\AgaP_AGAP009137
5 of 12
No
Yes
Agam\AgaP_AGAP005752
4 of 12
No
Yes
Agam\AgaP_AGAP007920
4 of 12
No
No
Agam\AgaP_AGAP008404
4 of 12
No
No
Agam\AgaP_AGAP010334
4 of 12
No
No
Agam\AgaP_AGAP002327
3 of 12
No
No
Agam\AgaP_AGAP002449
3 of 12
No
No
Agam\AgaP_AGAP008401
3 of 12
No
No
Arabidopsis thaliana (thale-cress) (113)
Atha\UGT76E2
4 of 13
Yes
Yes
Atha\AT2G28080
3 of 13
No
Yes
Atha\AT3G02100
3 of 13
No
Yes
Atha\AT3G22250
3 of 13
No
Yes
Atha\AT3G46650
3 of 13
No
Yes
Atha\AT3G46680
3 of 13
No
Yes
Atha\AT3G46690
3 of 13
No
Yes
Atha\AT3G46700
3 of 13
No
Yes
Atha\AT3G46720
3 of 13
No
Yes
Atha\AT5G05880
3 of 13
No
Yes
Atha\AT5G05890
3 of 13
No
Yes
Atha\AT5G05900
3 of 13
No
Yes
Atha\AT5G17040
3 of 13
No
Yes
Atha\AT5G37950
3 of 13
No
Yes
Atha\AT5G38010
3 of 13
No
Yes
Atha\AT5G38040
3 of 13
No
Yes
Atha\UGT76B1
3 of 13
No
Yes
Atha\UGT76C1
3 of 13
No
No
Atha\UGT76C2
3 of 13
No
Yes
Atha\UGT76D1
3 of 13
No
Yes
Atha\UGT76E1
3 of 13
No
Yes
Atha\UGT76E11
3 of 13
No
Yes
Atha\UGT76E12
3 of 13
No
Yes
Atha\UGT78D1
3 of 13
No
Yes
Atha\UGT78D2
3 of 13
No
No
Atha\UGT78D3
3 of 13
No
Yes
Atha\UGT85A1
3 of 13
No
Yes
Atha\UGT85A2
3 of 13
No
Yes
Atha\UGT85A3
3 of 13
No
No
Atha\UGT85A4
3 of 13
No
Yes
Atha\UGT85A5
3 of 13
No
Yes
Atha\UGT85A7
3 of 13
No
Yes
Atha\AT1G05675
2 of 13
No
Yes
Atha\AT1G06000
2 of 13
No
Yes
Atha\AT1G51210
2 of 13
No
Yes
Atha\AT2G22590
2 of 13
No
No
Atha\AT2G30150
2 of 13
No
Yes
Atha\AT2G31790
2 of 13
No
No
Atha\AT2G36970
2 of 13
No
Yes
Atha\AT3G55700
2 of 13
No
Yes
Atha\AT3G55710
2 of 13
No
Yes
Atha\AT5G03490
2 of 13
No
Yes
Atha\AT5G49690
2 of 13
No
No
Atha\AT5G65550
2 of 13
No
No
Atha\UGT71B6
2 of 13
No
No
Atha\UGT71C5
2 of 13
No
No
Atha\UGT71D1
2 of 13
No
No
Atha\UGT73B3
2 of 13
No
No
Atha\UGT73B4
2 of 13
No
No
Atha\UGT73B5
2 of 13
No
No
Atha\UGT74B1
2 of 13
No
Yes
Atha\UGT74D1
2 of 13
No
Yes
Atha\UGT74E2
2 of 13
No
No
Atha\UGT74F1
2 of 13
No
Yes
Atha\UGT74F2
2 of 13
No
Yes
Atha\UGT75B1
2 of 13
No
No
Atha\UGT84A1
2 of 13
No
Yes
Atha\UGT84A3
2 of 13
No
Yes
Atha\UGT84B1
2 of 13
No
Yes
Atha\UGT87A2
2 of 13
No
No
Atha\UGT89B1
2 of 13
No
Yes
Atha\AT1G01390
1 of 13
No
No
Atha\AT1G10400
1 of 13
No
No
Atha\AT1G50580
1 of 13
No
No
Atha\AT1G64910
1 of 13
No
No
Atha\AT1G64920
1 of 13
No
No
Atha\AT2G16890
1 of 13
No
No
Atha\AT2G18560
1 of 13
No
No
Atha\AT2G18570
1 of 13
No
No
Atha\AT2G22930
1 of 13
No
No
Atha\AT2G29710
1 of 13
No
No
Atha\AT2G36770
1 of 13
No
No
Atha\AT2G36780
1 of 13
No
No
Atha\AT3G21790
1 of 13
No
No
Atha\AT3G29630
1 of 13
No
No
Atha\AT4G09500
1 of 13
No
No
Atha\AT4G14090
1 of 13
No
No
Atha\AT4G15260
1 of 13
No
No
Atha\AT4G27560
1 of 13
No
No
Atha\AT4G27570
1 of 13
No
No
Atha\AT4G36770
1 of 13
No
No
Atha\AT5G12890
1 of 13
No
No
Atha\AT5G14860
1 of 13
No
No
Atha\AT5G53990
1 of 13
No
No
Atha\AT5G54010
1 of 13
No
No
Atha\DOGT1
1 of 13
No
No
Atha\GT72B1
1 of 13
No
No
Atha\HYR1
1 of 13
No
No
Atha\IAGLU
1 of 13
No
No
Atha\UF3GT
1 of 13
No
No
Atha\UGT71B1
1 of 13
No
No
Atha\UGT71B5
1 of 13
No
No
Atha\UGT71B8
1 of 13
No
No
Atha\UGT71C1
1 of 13
No
No
Atha\UGT71C2
1 of 13
No
No
Atha\UGT71C3
1 of 13
No
No
Atha\UGT71C4
1 of 13
No
No
Atha\UGT72B3
1 of 13
No
No
Atha\UGT72E1
1 of 13
No
No
Atha\UGT72E2
1 of 13
No
No
Atha\UGT72E3
1 of 13
No
No
Atha\UGT73B1
1 of 13
No
No
Atha\UGT73B2
1 of 13
No
No
Atha\UGT73C1
1 of 13
No
No
Atha\UGT73C2
1 of 13
No
No
Atha\UGT73C6
1 of 13
No
No
Atha\UGT73C7
1 of 13
No
No
Atha\UGT73D1
1 of 13
No
No
Atha\UGT75B2
1 of 13
No
No
Atha\UGT84A2
1 of 13
No
No
Atha\UGT84A4
1 of 13
No
No
Atha\UGT84B2
1 of 13
No
No
Atha\UGT88A1
1 of 13
No
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Ugt35B1. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (34)
Ugt35A1
12 of 13
Ugt35C1
12 of 13
Ugt35D1
12 of 13
Ugt35E1
12 of 13
Ugt35E2
12 of 13
Ugt302C1
11 of 13
Ugt302E1
11 of 13
Ugt302K1
11 of 13
Ugt303A1
11 of 13
Ugt303B1
11 of 13
Ugt303B2
11 of 13
Ugt303B3
11 of 13
Ugt36D1
10 of 13
Ugt36E1
10 of 13
Ugt36F1
10 of 13
Ugt49B1
10 of 13
Ugt49C1
10 of 13
Ugt304A1
10 of 13
Ugt49B2
9 of 13
Ugt301D1
9 of 13
Ugt36A1
8 of 13
Ugt37A3
8 of 13
Ugt37C1
8 of 13
Ugt37C2
8 of 13
Ugt37E1
8 of 13
Ugt316A1
8 of 13
Ugt37A1
7 of 13
Ugt37A2
7 of 13
Ugt37B1
7 of 13
Ugt37D1
7 of 13
Ugt50B3
7 of 13
Ugt305A1
6 of 13
Ugt307A1
6 of 13
Ugt317A1
6 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 2 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    UGT2A3; UDP glucuronosyltransferase family 2 member A3
    11 of 14
    616382
        UGT1A1; UDP glucuronosyltransferase family 1 member A1
        10 of 14
        191740
        UGT1A4; UDP glucuronosyltransferase family 1 member A4
        10 of 14
        606429
            UGT1A6; UDP glucuronosyltransferase family 1 member A6
            10 of 14
            606431
                UGT1A7; UDP glucuronosyltransferase family 1 member A7
                10 of 14
                606432
                    UGT1A8; UDP glucuronosyltransferase family 1 member A8
                    10 of 14
                    606433
                        UGT1A9; UDP glucuronosyltransferase family 1 member A9
                        10 of 14
                        606434
                            UGT1A10; UDP glucuronosyltransferase family 1 member A10
                            10 of 14
                            606435
                                UGT2A1; UDP glucuronosyltransferase family 2 member A1 complex locus
                                10 of 14
                                604716
                                    UGT2B4; UDP glucuronosyltransferase family 2 member B4
                                    10 of 14
                                    600067
                                        UGT2B7; UDP glucuronosyltransferase family 2 member B7
                                        10 of 14
                                        600068
                                            UGT2B10; UDP glucuronosyltransferase family 2 member B10
                                            10 of 14
                                            600070
                                                UGT2B11; UDP glucuronosyltransferase family 2 member B11
                                                10 of 14
                                                603064
                                                    UGT2B15; UDP glucuronosyltransferase family 2 member B15
                                                    10 of 14
                                                    600069
                                                        UGT2B17; UDP glucuronosyltransferase family 2 member B17
                                                        10 of 14
                                                        601903
                                                          UGT2B28; UDP glucuronosyltransferase family 2 member B28
                                                          10 of 14
                                                          606497
                                                              UGT1A3; UDP glucuronosyltransferase family 1 member A3
                                                              9 of 14
                                                              606428
                                                                  UGT1A5; UDP glucuronosyltransferase family 1 member A5
                                                                  9 of 14
                                                                  606430
                                                                      UGT2A2; UDP glucuronosyltransferase family 2 member A2
                                                                      9 of 14
                                                                      619809
                                                                          UGT8; UDP glycosyltransferase 8
                                                                          8 of 14
                                                                          601291
                                                                              UGT3A1; UDP glycosyltransferase family 3 member A1
                                                                              5 of 14
                                                                              616383
                                                                                  UGT3A2; UDP glycosyltransferase family 3 member A2
                                                                                  5 of 14
                                                                                  616384
                                                                                      Functional Complementation Data
                                                                                      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                                                                      Interactions
                                                                                      Summary of Physical Interactions
                                                                                      Interaction Browsers
                                                                                      View in FlyBase Interactions Browser   View in MIST tool (external link)
                                                                                      Please see the Physical Interaction reports below for full details
                                                                                      protein-protein
                                                                                      Physical Interaction
                                                                                      Assay
                                                                                      References
                                                                                      Ugt35B1 - Lsd-2
                                                                                      anti tag coimmunoprecipitation, Identification by mass spectrometry, anti tag western blot
                                                                                      (Sheng et al., 2025)
                                                                                      Summary of Genetic Interactions
                                                                                      Interaction Browsers
                                                                                      Starting gene(s)
                                                                                      Interaction type
                                                                                      Interacting gene(s)
                                                                                      Reference
                                                                                      Starting gene(s)
                                                                                      Interaction type
                                                                                      Interacting gene(s)
                                                                                      Reference
                                                                                      External Data
                                                                                      Linkouts
                                                                                      DroID - A comprehensive database of gene and protein interactions.
                                                                                      Pathways
                                                                                      Signaling Pathways (FlyBase)
                                                                                      Metabolic Pathways
                                                                                      FlyBase
                                                                                      External Links
                                                                                      External Data
                                                                                      Linkouts
                                                                                      Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                                                                      Class of Gene
                                                                                      Genomic Location and Detailed Mapping Data
                                                                                      Chromosome (arm)
                                                                                      3R
                                                                                      Recombination map
                                                                                      3-50
                                                                                      Cytogenetic map
                                                                                      86D5-86D5
                                                                                      Sequence location
                                                                                      FlyBase Computed Cytological Location
                                                                                      Cytogenetic map
                                                                                      Evidence for location
                                                                                      86D5-86D5
                                                                                      Limits computationally determined from genome sequence between P{EP}EP3340EP3340 and P{PZ}tho1&P{PZ}l(3)0462905275
                                                                                      Experimentally Determined Cytological Location
                                                                                      Cytogenetic map
                                                                                      Notes
                                                                                      References
                                                                                      86D1-86D2
                                                                                      (Wang, 1998.12.24)
                                                                                      86C-86D
                                                                                      (determined by in situ hybridisation)
                                                                                      (Wang et al., 1999)
                                                                                      Experimentally Determined Recombination Data
                                                                                      Location

                                                                                      3-50

                                                                                      (FlyBase, 2016)

                                                                                      3-47.6

                                                                                      (Comeron et al., 2012)
                                                                                      Left of (cM)
                                                                                      Right of (cM)
                                                                                      Notes
                                                                                      Stocks and Reagents
                                                                                      Stocks (8)
                                                                                      Genomic Clones (9)
                                                                                       

                                                                                      Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                                                                                      cDNA Clones (12)
                                                                                       

                                                                                      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                                                                                      cDNA clones, fully sequenced
                                                                                      BDGP DGC clones
                                                                                      Other clones
                                                                                        Drosophila Genomics Resource Center cDNA clones

                                                                                        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                                                                        cDNA Clones, End Sequenced (ESTs)
                                                                                        BDGP DGC clones
                                                                                        Other clones
                                                                                        RNAi and Array Information
                                                                                        Linkouts
                                                                                        DRSC - Results frm RNAi screens
                                                                                        Antibody Information
                                                                                        Laboratory Generated Antibodies
                                                                                         
                                                                                        Commercially Available Antibodies
                                                                                         
                                                                                        Cell Line Information
                                                                                        Publicly Available Cell Lines
                                                                                         
                                                                                          Other Stable Cell Lines
                                                                                           
                                                                                            Other Comments

                                                                                            Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days.

                                                                                            (Claridge-Chang et al., 2001)

                                                                                            Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day.

                                                                                            (McDonald and Rosbash, 2001)
                                                                                            Relationship to Other Genes
                                                                                            Source for database merge of

                                                                                            Source for merge of: Ugt35b Ugt86Db

                                                                                            (Bayraktaroglu, 2000.11.2)
                                                                                            Additional comments
                                                                                            Nomenclature History
                                                                                            Source for database identify of

                                                                                            Source for identity of: Ugt35B1 Ugt35b

                                                                                            (Bock et al., 2018)
                                                                                            Nomenclature comments

                                                                                            UGT gene nomenclature follows that of the UGT Nomenclature Committee and, despite the superficial resemblance in some cases, does not indicate the cytological location of the gene. Rather, the first number specifies a UGT family, the letter then specifies a subfamily, and the final number specifies an individual member.

                                                                                            (Bock et al., 2018)
                                                                                            Etymology
                                                                                            Synonyms and Secondary IDs (15)
                                                                                            Datasets (0)
                                                                                            Study focus (0)
                                                                                            Experimental Role
                                                                                            Project
                                                                                            Project Type
                                                                                            Title
                                                                                            Study result (0)
                                                                                            Result
                                                                                            Result Type
                                                                                            Title
                                                                                            External Crossreferences and Linkouts ( 35 )
                                                                                            Sequence Crossreferences
                                                                                            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                                                                            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                                                                            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                                                                            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                                                                            UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                                                                                            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                                                                                            Other crossreferences
                                                                                            AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                                                                                            BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                                                                                            DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                                                                                            EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                                                                                            FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                                                                                            FlyMine - An integrated database for Drosophila genomics
                                                                                            InterPro - A database of protein families, domains and functional sites
                                                                                            KEGG Genes - Molecular building blocks of life in the genomic space.
                                                                                            MARRVEL_MODEL - MARRVEL (model organism gene)
                                                                                            Linkouts
                                                                                            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                                                                            DroID - A comprehensive database of gene and protein interactions.
                                                                                            DRSC - Results frm RNAi screens
                                                                                            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                                                                            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                                                                                            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                                                                                            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                                                                            Flygut - An atlas of the Drosophila adult midgut
                                                                                            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                                                                            References (66)