FlyBase Gene Report: Dmel\Ugt37D1

General Information

Symbol

Dmel\Ugt37D1

Species

D. melanogaster

Name

UDP-glycosyltransferase family 37 member D1

Annotation Symbol

CG17932

Feature Type

protein_coding_gene

FlyBase ID

FBgn0040260

Gene Model Status

Current

Stock Availability

7 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Ugt36Bc

Key Links

Genomic Location

Cytogenetic map

36B1-36B1

Sequence location

2L:16,799,025..16,801,584 [+]

Recombination map

2-53

RefSeq locus

NT_033779 REGION:16799025..16801584

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (2 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables UDP-glycosyltransferase activity

inferred from sequence model

(Ahn and Marygold, 2021)

inferred from electronic annotation with InterPro:IPR002213

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN005360456

(GO Reference Genome Project, 2011-)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in endoplasmic reticulum membrane

inferred from sequence model

(Ahn and Marygold, 2021)

Gene Group (FlyBase)

GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES -: The GT1 family of UDP-glycosyltransferases (UGTs) catalyze the transfer the glycosyl group from a nucleotide sugar, such as UDP-glucuronic acid, UDP-galactose, UDP-glucose or UDP-xylose, to a variety of small hydrophobic acceptor molecules (aglycones), resulting in more hydrophilic compounds that are efficiently excreted. Mammalian/vertebrate UGTs mainly use UDP-glucuronic acid as the sugar donor, whereas invertebrates and plants appear to use UDP-glucose as the main donor. Insect UGTs play a major role in the detoxification of substrates, cuticle formation, pigmentation and olfaction. The GT1 family is defined by a common protein structure and signature sequence of 44 amino acids responsible for binding the UDP moiety of the sugar donor. (Adapted from FBrf0152079 and PMID:26453144).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Ugt37D1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VJH8)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.45

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Ugt37D1-RA

FBtr0080911

NM_144370

1934

543

Ugt37D1-RB

FBtr0080912

NM_165193

1954

543

Ugt37D1-RC

FBtr0344850

NM_001299060

1738

543

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Ugt37D1-PA

FBpp0080468

60.5

543

10.04

FBpp0080469

60.5

543

10.04

FBpp0311165

60.5

543

10.04

Q9VJH8

NP_001285989

AHN54503

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

543 aa isoforms: Ugt37D1-PA, Ugt37D1-PB, Ugt37D1-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ugt37D1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.64

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 7 -- 8

posterior endoderm

(Fisher et al., 2012)

yolk nucleus

(Fisher et al., 2012)

embryonic stage 9 -- 10

anterior endoderm

(Fisher et al., 2012)

crystal cell primordium

Comment: reported as crystal cell specific anlage

(Fisher et al., 2012)

head mesoderm

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

yolk nucleus

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

procrystal cell

(Fisher et al., 2012)

somatic muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)

trunk visceral muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)

yolk nucleus

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic/larval crystal cell

(Fisher et al., 2012)

dorsal pharyngeal muscle cell

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

embryonic/larval midgut interstitial cell

(Fisher et al., 2012)

larval muscle system

(Fisher et al., 2012)

larval somatic muscle cell

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Ugt37D1 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Ugt37D1

View exonic expression by tissue for Dmel\Ugt37D1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0040260

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

53511/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0040260

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0040260

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0040260

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17932

Flygut - An atlas of the Drosophila adult midgut

FBgn0040260

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Ugt37D1

Stages(s) 7-8
Stages(s) 9-10
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 2 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Ugt37D1

Transgenic constructs containing regulatory region of Ugt37D1

Aberrations (Deficiencies and Duplications) ( 3 )

Inferred from experimentation ( 3 )

Gene disrupted in

Df(2L)Exel6039

(Ryder, 2004.4.26)

Df(2L)Exel7067

(Ryder, 2004.4.26)

Df(2L)Exel8036

(Ryder, 2004.4.26)

Inferred from location ( 12 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Ugt37D1^GD1748

viable, with Scer\GAL4^Mef2.PR

Ugt37D1^GD1748

viable, with Scer\GAL4^pnr-MD237

Ugt37D1^GD1748

viable, with Scer\GAL4^tin.CΔ4

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (22)

Hsap\UGT1A3

6 of 14

Yes

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

4 of 14

4 of 14

4 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (19)

Rnor\RGD1559459

5 of 14

Yes

Rnor\Ugt1a2

5 of 14

Yes

Rnor\Ugt1a5

5 of 14

Yes

Rnor\Ugt2a3

5 of 14

Yes

Rnor\Ugt2b15

5 of 14

Yes

Rnor\Ugt2b35

5 of 14

Yes

Rnor\Ugt8

5 of 14

Yes

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

3 of 14

1 of 14

Mus musculus (laboratory mouse) (22)

Mmus\Ugt1a2

6 of 14

Yes

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

4 of 14

4 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (14)

Xtro\ugt1a1

4 of 13

Yes

Xtro\ugt1a6

4 of 13

Yes

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\LOC100493420

1 of 13

Xtro\rps15

1 of 13

Xtro\XB5897453

1 of 13

Yes

Danio rerio (Zebrafish) (34)

Drer\ugt2a5

5 of 14

Yes

Drer\ugt2b3

5 of 14

Yes

Drer\ugt5a1

5 of 14

Yes

Drer\ugt5a2

5 of 14

Yes

Drer\ugt5b2

5 of 14

Yes

Drer\ugt5b3

5 of 14

Yes

Drer\ugt5b4

5 of 14

Yes

Drer\ugt5c1

5 of 14

Yes

Drer\ugt5c2

5 of 14

Yes

Drer\ugt5c3

5 of 14

Yes

Drer\ugt5d1

5 of 14

Yes

Drer\ugt5e1

5 of 14

Yes

Drer\ugt5g1

5 of 14

Yes

Drer\ugt5g2

5 of 14

Yes

Drer\ugt8

5 of 14

Yes

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

2 of 14

2 of 14

Yes

Drer\ugt1a4

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (72)

Cele\ugt-47

6 of 14

Yes

Cele\ugt-49

6 of 14

Yes

Cele\ugt-50

6 of 14

Yes

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

1 of 14

Yes

Cele\T19H12.12

1 of 14

Cele\Y43D4A.2

1 of 14

Anopheles gambiae (African malaria mosquito) (24)

Agam\AgaP_AGAP007589

11 of 12

Yes

Agam\AgaP_AGAP011564

11 of 12

Yes

Agam\AgaP_AGAP007588

9 of 12

Agam\AgaP_AGAP002783

6 of 12

Yes

6 of 12

6 of 12

6 of 12

5 of 12

5 of 12

Yes

Agam\AgaP_AGAP005751

5 of 12

Yes

Agam\AgaP_AGAP005753

5 of 12

Yes

Agam\AgaP_AGAP005754

5 of 12

Yes

Agam\AgaP_AGAP006775

5 of 12

Agam\AgaP_AGAP007028

5 of 12

Agam\AgaP_AGAP009137

5 of 12

Yes

Agam\AgaP_AGAP005163

4 of 12

Agam\AgaP_AGAP005752

4 of 12

Yes

4 of 12

4 of 12

4 of 12

3 of 12

3 of 12

3 of 12

3 of 12

Arabidopsis thaliana (thale-cress) (113)

Atha\AT5G65550

4 of 13

Yes

Atha\AT2G22590

3 of 13

Yes

Atha\AT5G49690

3 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Ugt37D1. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (34)

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

10 of 13

10 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

6 of 13

6 of 13

6 of 13

5 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

UGT1A3; UDP glucuronosyltransferase family 1 member A3

6 of 14

606428

UGT1A1; UDP glucuronosyltransferase family 1 member A1

5 of 14

191740

UGT1A4; UDP glucuronosyltransferase family 1 member A4

5 of 14

606429

UGT1A5; UDP glucuronosyltransferase family 1 member A5

5 of 14

606430

UGT1A6; UDP glucuronosyltransferase family 1 member A6

5 of 14

606431

UGT1A7; UDP glucuronosyltransferase family 1 member A7

5 of 14

606432

UGT1A8; UDP glucuronosyltransferase family 1 member A8

5 of 14

606433

UGT1A9; UDP glucuronosyltransferase family 1 member A9

5 of 14

606434

UGT1A10; UDP glucuronosyltransferase family 1 member A10

5 of 14

606435

UGT2A1; UDP glucuronosyltransferase family 2 member A1 complex locus

5 of 14

604716

UGT2A3; UDP glucuronosyltransferase family 2 member A3

5 of 14

616382

UGT2B4; UDP glucuronosyltransferase family 2 member B4

5 of 14

600067

UGT2B7; UDP glucuronosyltransferase family 2 member B7

5 of 14

600068

UGT2B10; UDP glucuronosyltransferase family 2 member B10

5 of 14

600070

UGT2B11; UDP glucuronosyltransferase family 2 member B11

5 of 14

603064

UGT2B15; UDP glucuronosyltransferase family 2 member B15

5 of 14

600069

UGT2B17; UDP glucuronosyltransferase family 2 member B17

5 of 14

601903

BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 12; BMND12

UGT2B28; UDP glucuronosyltransferase family 2 member B28

5 of 14

606497

UGT8; UDP glycosyltransferase 8

5 of 14

601291

UGT2A2; UDP glucuronosyltransferase family 2 member A2

4 of 14

619809

UGT3A1; UDP glycosyltransferase family 3 member A1

4 of 14

616383

UGT3A2; UDP glycosyltransferase family 3 member A2

4 of 14

616384

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0040260

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-53

Cytogenetic map

36B1-36B1

Sequence location

2L:16,799,025..16,801,584 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

36B1-36B1

Limits computationally determined from genome sequence between P{lacW}Mhc^k10423&P{lacW}Cas^k03902 and P{lacW}Aac11^k06710

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-53

(FlyBase, 2016)

2-51.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

64567

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05586}attP40

NIG-Fly

17932R-4

P{NIG.17932R}4

M2L-2183

y¹ w¹¹¹⁸; Ugt37D1^SK1 P{neoFRT}40A/CyO-Tb

M2L-2184

y¹ w¹¹¹⁸; Ugt37D1^SK6 P{neoFRT}40A/CyO-Tb

2LG-1733

y² VhaAC39-1^cho-1 v¹; P{U6-Ugt37D1.NIG.sgRNA}attP40/CyO

VDRC

v101859

P{KK110058}VIE-260B

v47655

w¹¹¹⁸; P{GD16878}v47655

Genomic Clones (8)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (28)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

RE03785

Other clones

FI03416

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0040260

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0040260

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; decreased expression in per⁰¹, tim⁰¹ and Clk^Jrk background.

(Claridge-Chang et al., 2001)

Relationship to Other Genes

Source for database merge of

Source for merge of: Ugt36Bc CG17932

(Bayraktaroglu, 2000.11.2)

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: Ugt37D1 Ugt36Bc

(Bock et al., 2018)

Nomenclature comments

UGT gene nomenclature follows that of the UGT Nomenclature Committee and, despite the superficial resemblance in some cases, does not indicate the cytological location of the gene. Rather, the first number specifies a UGT family, the letter then specifies a subfamily, and the final number specifies an individual member.

(Bock et al., 2018)

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

AC 005121C

(Theopold et al., 1999)

CG17932

(National Institute of Genetics Fly Stocks, 2022-, Palu and Thummel, 2016, Ahn et al., 2012, Keleman et al., 2009.8.5, Perkins et al., 2009, Luque and O'Reilly, 2002)

UGT37D1

(Ahn et al., 2012)

Ugt36Bc

(Mossman et al., 2016, Van Bortle et al., 2015, DeSalvo et al., 2014, Zhang et al., 2014, Chen et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Blauwkamp et al., 2008)

Ugt37D1

(Kim et al., 2024, Ahn and Marygold, 2021, Bock et al., 2018)

Name Synonyms

UDP-glycosyltransferase 36Bc

UDP-glycosyltransferase family 37 member D1

Ugt36Bc

Secondary FlyBase IDs

FBgn0032606

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 56 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

53511

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VJH8

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VJH8

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0040260

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

53511/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0040260

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0040260

FlyMine - An integrated database for Drosophila genomics

FBgn0040260

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG17932

MARRVEL_MODEL - MARRVEL (model organism gene)

53511

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0040260

DroID - A comprehensive database of gene and protein interactions.

FBgn0040260

DRSC - Results frm RNAi screens

FBgn0040260

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0040260

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0040260

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17932

Flygut - An atlas of the Drosophila adult midgut

FBgn0040260

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (46)

The following external sites may use different assemblies or annotations than FlyBase.

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