FlyBase Gene Report: Dmel\Ugt302K1

General Information

Symbol

Dmel\Ugt302K1

Species

D. melanogaster

Name

UDP-glycosyltransferase family 302 member K1

Annotation Symbol

CG6658

Feature Type

protein_coding_gene

FlyBase ID

FBgn0040251

Gene Model Status

Current

Stock Availability

5 publicly available

Gene Summary

UDP-glycosyltransferase family 302 member K1 (Ugt302K1) encodes a UDP-glucosyltransferase. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Ugt86Di

Key Links

Genomic Location

Cytogenetic map

86D5-86D5

Sequence location

3R:11,151,026..11,153,849 [-]

Recombination map

3-50

RefSeq locus

NT_033777 REGION:11151026..11153849

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (2 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables UDP-glycosyltransferase activity

inferred from electronic annotation with InterPro:IPR002213

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN005360456

(GO Reference Genome Project, 2011-)

inferred from sequence model

(Ahn and Marygold, 2021)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in endoplasmic reticulum membrane

inferred from sequence model

(Ahn and Marygold, 2021)

Gene Group (FlyBase)

GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

UDP-glycosyltransferase family 302 member K1 (Ugt302K1) encodes a UDP-glucosyltransferase. [Date last reviewed: 2019-03-14]

Gene Group (FlyBase)

GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES -: The GT1 family of UDP-glycosyltransferases (UGTs) catalyze the transfer the glycosyl group from a nucleotide sugar, such as UDP-glucuronic acid, UDP-galactose, UDP-glucose or UDP-xylose, to a variety of small hydrophobic acceptor molecules (aglycones), resulting in more hydrophilic compounds that are efficiently excreted. Mammalian/vertebrate UGTs mainly use UDP-glucuronic acid as the sugar donor, whereas invertebrates and plants appear to use UDP-glucose as the main donor. Insect UGTs play a major role in the detoxification of substrates, cuticle formation, pigmentation and olfaction. The GT1 family is defined by a common protein structure and signature sequence of 44 amino acids responsible for binding the UDP moiety of the sugar donor. (Adapted from FBrf0152079 and PMID:26453144).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Ugt302K1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VGT5)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.47

Gene model reviewed during 5.56

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Ugt302K1-RA

FBtr0082378

NM_144363

1675

519

Ugt302K1-RB

FBtr0346101

NM_001300352

2556

519

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Ugt302K1-PA

FBpp0081854

59.0

519

9.34

FBpp0311934

59.0

519

9.34

Q9VGT5

NP_001287281

AHN57280

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

519 aa isoforms: Ugt302K1-PA, Ugt302K1-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VGT5

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ugt302K1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Ugt86Di_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.50

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Ugt302K1 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Ugt302K1

View exonic expression by tissue for Dmel\Ugt302K1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

53502/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0040251

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0040251

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0040251

Flygut - An atlas of the Drosophila adult midgut

FBgn0040251

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Ugt302K1

Transgenic constructs containing regulatory region of Ugt302K1

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3R)Exel7306

(Ryder, 2004.4.26)

Inferred from location ( 9 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

Ugt302K1^e00862

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Ugt302K1^GD3631

viable, with Scer\GAL4^Mef2.PR

Ugt302K1^GD3631

viable, with Scer\GAL4^pnr-MD237

Ugt302K1^GD3631

viable, with Scer\GAL4^tin.CΔ4

Ugt302K1^GD3631

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (22)

Hsap\UGT1A1

10 of 14

Yes

Hsap\UGT1A4

10 of 14

Yes

Hsap\UGT1A6

10 of 14

Yes

Hsap\UGT1A7

10 of 14

Yes

Hsap\UGT1A8

10 of 14

Yes

Hsap\UGT1A9

10 of 14

Yes

Hsap\UGT1A10

10 of 14

Yes

Hsap\UGT2A1

10 of 14

Yes

Hsap\UGT2A3

10 of 14

Yes

Hsap\UGT2B4

10 of 14

Yes

Hsap\UGT2B7

10 of 14

Yes

Hsap\UGT2B10

10 of 14

Yes

Hsap\UGT2B11

10 of 14

Yes

Hsap\UGT2B15

10 of 14

Yes

Hsap\UGT2B17

10 of 14

Yes

Hsap\UGT2B28

10 of 14

Yes

Hsap\UGT1A3

9 of 14

Yes

Hsap\UGT1A5

9 of 14

Yes

Hsap\UGT2A2

9 of 14

Yes

Hsap\UGT8

8 of 14

Yes

Hsap\UGT3A1

5 of 14

Yes

Hsap\UGT3A2

5 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (19)

Rnor\RGD1559459

10 of 14

Yes

Rnor\Ugt2b15

10 of 14

Yes

Rnor\Ugt2b35

10 of 14

Yes

Rnor\Ugt1a1

9 of 14

Rnor\Ugt1a5

9 of 14

Yes

Rnor\Ugt1a7c

9 of 14

Yes

Rnor\Ugt2a3

9 of 14

Rnor\Ugt2b17

9 of 14

Yes

Rnor\Ugt2b37

9 of 14

Yes

Rnor\Ugt1a2

8 of 14

Yes

Rnor\Ugt1a3

8 of 14

Yes

Rnor\Ugt1a6

8 of 14

Yes

Rnor\Ugt1a8

8 of 14

Yes

Rnor\Ugt2a1

8 of 14

Yes

Rnor\Ugt2b7

8 of 14

Yes

Rnor\Ugt2b

8 of 14

Yes

Rnor\Ugt8

8 of 14

Yes

Rnor\Ugt3a2

5 of 14

Yes

Rnor\Ugt2b10

2 of 14

Yes

Mus musculus (laboratory mouse) (22)

Mmus\Ugt1a7c

11 of 14

Yes

Mmus\Ugt1a1

10 of 14

Yes

Mmus\Ugt1a2

10 of 14

Yes

Mmus\Ugt1a5

10 of 14

Yes

Mmus\Ugt1a6a

10 of 14

Yes

Mmus\Ugt1a6b

10 of 14

Yes

Mmus\Ugt1a8

10 of 14

Yes

Mmus\Ugt1a9

10 of 14

Yes

Mmus\Ugt2a1

10 of 14

Yes

Mmus\Ugt2a3

10 of 14

Mmus\Ugt2b1

10 of 14

Yes

Mmus\Ugt2b5

10 of 14

Yes

Mmus\Ugt2b34

10 of 14

Yes

Mmus\Ugt2b35

10 of 14

Yes

Mmus\Ugt2b36

10 of 14

Yes

Mmus\Ugt2b37

10 of 14

Yes

Mmus\Ugt2b38

10 of 14

Yes

Mmus\Ugt2a2

9 of 14

Yes

Mmus\Ugt8a

9 of 14

Yes

Mmus\Ugt3a1

5 of 14

Yes

Mmus\Ugt3a2

5 of 14

Yes

Mmus\Ugt1a10

3 of 14

Yes

Xenopus tropicalis (Western clawed frog) (15)

Xtro\ugt1a1

8 of 13

Yes

Xtro\ugt1a6

8 of 13

Yes

5 of 13

4 of 13

3 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\LOC100493420

1 of 13

Xtro\rps15

1 of 13

Xtro\XB5897453

1 of 13

Yes

Danio rerio (Zebrafish) (34)

Drer\ugt2a5

10 of 14

Yes

Drer\ugt2b3

10 of 14

Yes

Drer\ugt5a1

10 of 14

Yes

Drer\ugt5a2

10 of 14

Yes

Drer\ugt5c1

10 of 14

Yes

Drer\ugt5c2

10 of 14

Yes

Drer\ugt5c3

10 of 14

Yes

Drer\ugt5d1

10 of 14

Yes

Drer\ugt5g2

10 of 14

Yes

Drer\ugt1ab

9 of 14

Drer\ugt5b2

9 of 14

Yes

Drer\ugt5b3

9 of 14

Yes

Drer\ugt5b4

9 of 14

Yes

Drer\ugt5e1

9 of 14

Yes

Drer\ugt5g1

9 of 14

Yes

8 of 14

8 of 14

8 of 14

8 of 14

Yes

Drer\ugt5f1

8 of 14

Yes

Drer\ugt8

8 of 14

Yes

Drer\ugt1b1

2 of 14

Yes

Drer\ugt1b2

2 of 14

Yes

Drer\ugt1b3

2 of 14

Yes

Drer\ugt1b4

2 of 14

Yes

Drer\ugt1b7

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Drer\ugt1a4

1 of 14

Yes

Drer\ugt1b5

1 of 14

Yes

Drer\ugt2b6

1 of 14

Drer\ugt5b1

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (71)

Cele\ugt-20

7 of 14

Yes

Cele\ugt-22

7 of 14

Yes

Cele\ugt-26

7 of 14

Yes

Cele\ugt-58

7 of 14

Yes

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

Yes

6 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

4 of 14

4 of 14

4 of 14

4 of 14

4 of 14

Yes

4 of 14

4 of 14

4 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

Anopheles gambiae (African malaria mosquito) (24)

Agam\AgaP_AGAP006222

11 of 12

Yes

Agam\AgaP_AGAP007029

11 of 12

Yes

Agam\AgaP_AGAP006223

9 of 12

Yes

Agam\AgaP_AGAP007028

7 of 12

Yes

Agam\AgaP_AGAP007588

7 of 12

Agam\AgaP_AGAP011564

7 of 12

Agam\AgaP_AGAP002783

6 of 12

Yes

Agam\AgaP_AGAP006775

6 of 12

Yes

6 of 12

6 of 12

5 of 12

5 of 12

Yes

Agam\AgaP_AGAP005751

5 of 12

Yes

Agam\AgaP_AGAP005753

5 of 12

Yes

Agam\AgaP_AGAP005754

5 of 12

Yes

Agam\AgaP_AGAP007990

5 of 12

Agam\AgaP_AGAP009137

5 of 12

Yes

Agam\AgaP_AGAP002449

4 of 12

Agam\AgaP_AGAP005752

4 of 12

Yes

4 of 12

4 of 12

3 of 12

3 of 12

3 of 12

Arabidopsis thaliana (thale-cress) (113)

Atha\AT2G28080

3 of 13

Yes

Atha\AT3G02100

3 of 13

Yes

Atha\AT3G22250

3 of 13

Yes

Atha\AT3G46650

3 of 13

Yes

Atha\AT3G46680

3 of 13

Yes

Atha\AT3G46690

3 of 13

Yes

Atha\AT3G46700

3 of 13

Yes

Atha\AT3G46720

3 of 13

Yes

Atha\AT5G05880

3 of 13

Yes

Atha\AT5G05890

3 of 13

Yes

Atha\AT5G05900

3 of 13

Yes

Atha\AT5G17040

3 of 13

Yes

Atha\AT5G37950

3 of 13

Yes

Atha\AT5G38010

3 of 13

Yes

Atha\AT5G38040

3 of 13

Yes

Atha\UGT76B1

3 of 13

Yes

Atha\UGT76C1

3 of 13

Yes

Atha\UGT76C2

3 of 13

Yes

Atha\UGT76D1

3 of 13

Yes

Atha\UGT76E1

3 of 13

Yes

Atha\UGT76E2

3 of 13

Yes

Atha\UGT76E11

3 of 13

Yes

Atha\UGT76E12

3 of 13

Yes

Atha\UGT78D1

3 of 13

Yes

Atha\UGT78D2

3 of 13

Yes

Atha\UGT78D3

3 of 13

Yes

Atha\UGT85A1

3 of 13

Yes

Atha\UGT85A2

3 of 13

Yes

Atha\UGT85A3

3 of 13

Yes

Atha\UGT85A4

3 of 13

Yes

Atha\UGT85A5

3 of 13

Yes

Atha\UGT85A7

3 of 13

Yes

Atha\AT1G05675

2 of 13

Yes

Atha\AT1G06000

2 of 13

Yes

Atha\AT1G51210

2 of 13

Yes

Atha\AT2G22590

2 of 13

Atha\AT2G30150

2 of 13

Yes

Atha\AT2G31790

2 of 13

Atha\AT2G36970

2 of 13

Yes

Atha\AT3G55700

2 of 13

Yes

Atha\AT3G55710

2 of 13

Yes

Atha\AT5G03490

2 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Yes

Atha\UGT74D1

2 of 13

Yes

Atha\UGT74E2

2 of 13

Atha\UGT74F1

2 of 13

Yes

Atha\UGT74F2

2 of 13

Yes

Atha\UGT75B1

2 of 13

Atha\UGT84A1

2 of 13

Yes

Atha\UGT84A3

2 of 13

Yes

Atha\UGT84B1

2 of 13

Yes

Atha\UGT87A2

2 of 13

Atha\UGT89B1

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Ugt302K1. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (34)

13 of 13

13 of 13

12 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

11 of 13

10 of 13

10 of 13

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

7 of 13

7 of 13

7 of 13

7 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

UGT1A1; UDP glucuronosyltransferase family 1 member A1

model of Gilbert syndrome

IEA

(FlyBase, 2019-)

model of Crigler-Najjar syndrome

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

UGT1A1; UDP glucuronosyltransferase family 1 member A1

10 of 14

191740

UGT1A4; UDP glucuronosyltransferase family 1 member A4

10 of 14

606429

UGT1A6; UDP glucuronosyltransferase family 1 member A6

10 of 14

606431

UGT1A7; UDP glucuronosyltransferase family 1 member A7

10 of 14

606432

UGT1A8; UDP glucuronosyltransferase family 1 member A8

10 of 14

606433

UGT1A9; UDP glucuronosyltransferase family 1 member A9

10 of 14

606434

UGT1A10; UDP glucuronosyltransferase family 1 member A10

10 of 14

606435

UGT2A1; UDP glucuronosyltransferase family 2 member A1 complex locus

10 of 14

604716

UGT2A3; UDP glucuronosyltransferase family 2 member A3

10 of 14

616382

UGT2B4; UDP glucuronosyltransferase family 2 member B4

10 of 14

600067

UGT2B7; UDP glucuronosyltransferase family 2 member B7

10 of 14

600068

UGT2B10; UDP glucuronosyltransferase family 2 member B10

10 of 14

600070

UGT2B11; UDP glucuronosyltransferase family 2 member B11

10 of 14

603064

UGT2B15; UDP glucuronosyltransferase family 2 member B15

10 of 14

600069

UGT2B17; UDP glucuronosyltransferase family 2 member B17

10 of 14

601903

BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 12; BMND12

UGT2B28; UDP glucuronosyltransferase family 2 member B28

10 of 14

606497

UGT1A3; UDP glucuronosyltransferase family 1 member A3

9 of 14

606428

UGT1A5; UDP glucuronosyltransferase family 1 member A5

9 of 14

606430

UGT2A2; UDP glucuronosyltransferase family 2 member A2

9 of 14

619809

UGT8; UDP glycosyltransferase 8

8 of 14

601291

UGT3A1; UDP glycosyltransferase family 3 member A1

5 of 14

616383

UGT3A2; UDP glycosyltransferase family 3 member A2

5 of 14

616384

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

RNA-protein

Physical Interaction

Assay

References

Ugt302K1 - AGO1

anti bait coimmunoprecipitation, quantitative reverse transcription pcr

(Hong et al., 2009)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0040251

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-50

Cytogenetic map

86D5-86D5

Sequence location

3R:11,151,026..11,153,849 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

86D5-86D5

Limits computationally determined from genome sequence between P{EP}EP3340^EP3340 and P{PZ}tho¹&P{PZ}l(3)04629⁰⁵²⁷⁵

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-50

(FlyBase, 2016)

3-47.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

17894

w¹¹¹⁸; PBac{RB}Ugt302K1^e00862/TM6B, Tb¹

64568

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05587}attP40

FlyORF

F002937

M{UAS-Ugt302K1.ORF.3xHA.GW}ZH-86Fb

VDRC

v104262

P{KK106449}VIE-260B

v8569

w¹¹¹⁸; P{GD3631}v8569

Genomic Clones (20)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (4)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP02928

Other clones

DPiM_IP02928

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0040251

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0040251

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: Ugt86Di CG6658

(Bayraktaroglu, 2000.11.2)

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: Ugt302K1 Ugt86Di

(Bock et al., 2018)

Nomenclature comments

UGT gene nomenclature follows that of the UGT Nomenclature Committee and, despite the superficial resemblance in some cases, does not indicate the cytological location of the gene. Rather, the first number specifies a UGT family, the letter then specifies a subfamily, and the final number specifies an individual member.

(Bock et al., 2018)

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

AC 006491I

(Theopold et al., 1999)

CG6658

(Ahn et al., 2012, Zhang et al., 2010, Hong et al., 2009, Keleman et al., 2009.8.5, Perkins et al., 2009, Jacobsen et al., 2006, Luque and O'Reilly, 2002)

UGT302K1

(Ahn et al., 2012)

Ugt302K1

(Meyer et al., 2024, Voutyraki et al., 2023, Ahn and Marygold, 2021, Dow et al., 2021, Bock et al., 2018)

Ugt86Di

(Sebastian et al., 2022, Marriage et al., 2014, Spradling et al., 2011, Mahapatra et al., 2010, Turner et al., 2008, Firth and Baker, 2007, Jacobsen et al., 2006)

Name Synonyms

UDP-glycosyltransferase 86Di

UDP-glycosyltransferase family 302 member K1

Ugt86Di

Secondary FlyBase IDs

FBgn0037863

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 50 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

53502

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AC006491

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VGT5

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VGT5

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VGT5

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

53502/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0040251

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0040251

FlyMine - An integrated database for Drosophila genomics

FBgn0040251

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG6658

MARRVEL_MODEL - MARRVEL (model organism gene)

53502

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0040251

DroID - A comprehensive database of gene and protein interactions.

FBgn0040251

DRSC - Results frm RNAi screens

FBgn0040251

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Ugt86Di_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0040251

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0040251

Flygut - An atlas of the Drosophila adult midgut

FBgn0040251

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (43)

The following external sites may use different assemblies or annotations than FlyBase.

-0.50

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