FlyBase Gene Report: Dmel\Zdhhc8

General Information

Symbol

Dmel\Zdhhc8

Species

D. melanogaster

Name

Zinc finger DHHC-type containing 8

Annotation Symbol

CG34449

Feature Type

protein_coding_gene

FlyBase ID

FBgn0085478

Gene Model Status

Current

Stock Availability

12 publicly available

Enzyme Name (EC)

protein S-acyltransferase (2.3.1.225)

Gene Summary

Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (By similarity). Regulates tissue growth possibly by regulating Ras64B protein stability (PubMed:30735487). May regulate CG34450 mRNA levels (PubMed:30735487). (UniProt, Q9W345)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

Dm_X:47283

Key Links

Genomic Location

Cytogenetic map

8D7-8D9

Sequence location

X:9,324,508..9,356,227 [-]

Recombination map

1-27

RefSeq locus

NC_004354 REGION:9324508..9356227

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (2 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables palmitoyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN000525808

(GO Reference Genome Project, 2011-)

inferred from electronic annotation with InterPro:IPR001594

(InterPro Project Members, 2004-)

enables protein-cysteine S-palmitoyltransferase activity

inferred from sequence or structural similarity with UniProtKB:Q9C0B5

(Gene Ontology Curators, 2002-)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

PALMITOYLTRANSFERASES

Protein Family (UniProt)

Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. (Q9W345)

Protein Signatures (InterPro)

Palmitoyltransferase, DHHC domain

Catalytic Activity (EC/Rhea)

protein-cysteine S-palmitoyltransferase activity

L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl- [protein] + CoA (2.3.1.225)

RHEA 36683:

Summaries

Gene Group (FlyBase)

PALMITOYLTRANSFERASES -: Palmitoyltransferases catalyze the post-translational addition of a palmitate moiety to a cysteine residue through a covalent thioester bond. (Adapted from FBrf0210485).

Protein Function (UniProtKB)

(UniProt, Q9W345)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Zdhhc8 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9W345)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Stop-codon suppression (UAA) postulated; FBrf0216884.

Gene model reviewed during 5.39

Gene model reviewed during 5.44

Gene model reviewed during 5.51

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Zdhhc8-RA

FBtr0112753

NM_167189

6294

934

Zdhhc8-RB

FBtr0112754

NM_001103451

4189

911

Zdhhc8-RC

FBtr0112755

NM_001103452

2342

500

Zdhhc8-RD

FBtr0308591

NM_001258663

6951

523

Zdhhc8-RE

FBtr0331304

NM_001272453

4144

1052

Zdhhc8-RF

FBtr0343028

NM_001298122

6176

852

Zdhhc8-RG

FBtr0343029

NM_001298123

6324

906

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Zdhhc8-PA

FBpp0111665

99.7

934

9.43

FBpp0111666

97.2

911

9.34

FBpp0111667

54.4

500

9.00

FBpp0300815

56.9

523

9.14

FBpp0303736

112.6

1052

9.56

FBpp0309780

91.4

852

9.27

FBpp0309781

96.7

906

9.47

X2JE99

NP_001285052

AHN59523

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Domain

The DHHC domain is required for palmitoyltransferase activity.

(UniProt, Q9W345)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Palmitoyltransferase, DHHC domain

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Zdhhc8 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG34449_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.11

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

larval central nervous system

(Bannan et al., 2008)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Zdhhc8 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Zdhhc8

View exonic expression by tissue for Dmel\Zdhhc8

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

31887/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085478

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085478

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085478

Flygut - An atlas of the Drosophila adult midgut

FBgn0085478

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 13 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Zdhhc8

Transgenic constructs containing regulatory region of Zdhhc8

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene partially disrupted in

Df(1)Zdhhc8^KO1

(Strassburger et al., 2019)

Inferred from location ( 17 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal - all die before end of larval stage

lethal - all die before end of larval stage (with Zdhhc8^KO1)

Zdhhc8^KO2

lethal - all die before end of larval stage (with Zdhhc8^KO2)

Zdhhc8^KO1

viable

Zdhhc8^d00976

Sterility

Allele

fertile

Zdhhc8^d00976

Other Phenotypes

Allele

abnormal body size | larval stage

Zdhhc8^KO1

abnormal developmental rate | larval stage

Zdhhc8^KO1

abnormal immune response | adult stage, with Scer\GAL4^Cg.PU

Zdhhc8^UAS.Tag:Myc

abnormal size | adult stage, with Scer\GAL4^en.PU

Zdhhc8^GD3294

abnormal size | adult stage, with Scer\GAL4^hh.PU

Zdhhc8^GD3294

majority die during second instar larval stage

Zdhhc8^KO1

visible | adult stage, with Scer\GAL4^ap.PU

visible | larval stage

Zdhhc8^KO1

Phenotype manifest in

Allele

wing, with Scer\GAL4^ap.PU

wing, with Scer\GAL4^en.PU

Zdhhc8^GD3294

wing, with Scer\GAL4^hh.PU

Zdhhc8^GD3294

wing vein, with Scer\GAL4^Tub.PU

Zdhhc8^GD3294

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (24)

Hsap\ZDHHC5

9 of 14

Yes

Hsap\ZDHHC8

9 of 14

Yes

4 of 14

4 of 14

4 of 14

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (21)

Rnor\Zdhhc5

9 of 14

Yes

Rnor\Zdhhc8

9 of 14

Yes

4 of 14

4 of 14

3 of 14

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

Mus musculus (laboratory mouse) (24)

Mmus\Zdhhc8

9 of 14

Yes

Mmus\Zdhhc5

8 of 14

Yes

4 of 14

4 of 14

4 of 14

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (18)

Xtro\zdhhc8

6 of 13

Yes

Xtro\zdhhc5

5 of 13

Yes

4 of 13

3 of 13

3 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (33)

Drer\zdhhc5b

11 of 14

Yes

Drer\zdhhc8b

10 of 14

Yes

Drer\zdhhc5a

9 of 14

Yes

4 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Drer\si:ch211-223a10.1

1 of 14

Drer\zdhhc4

1 of 14

Drer\zdhhc6

1 of 14

Drer\zdhhc8a

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (15)

Cele\dhhc-8

9 of 14

Yes

4 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (12)

Agam\AgaP_AGAP000567

10 of 12

Yes

3 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

Arabidopsis thaliana (thale-cress) (24)

Atha\AT2G40990

4 of 13

Yes

Atha\AT3G26935

4 of 13

Yes

Atha\AT3G48760

4 of 13

Yes

Atha\AT3G56920

4 of 13

Yes

Atha\AT3G56930

4 of 13

Yes

Atha\AT4G24630

4 of 13

Yes

Atha\AT5G05070

4 of 13

Yes

Atha\AT5G41060

4 of 13

Yes

Atha\AT5G50020

4 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Saccharomyces cerevisiae (Brewer's yeast) (7)

Scer\ERF2

5 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (5)

Spom\erf2

4 of 12

Yes

Spom\swf1

3 of 12

Yes

Spom\akr1

2 of 12

Spom\pfa3

2 of 12

Spom\pfa5

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Zdhhc8. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (24)

app

6 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

ZDHHC5; zDHHC palmitoyltransferase 5

9 of 14

614586

ZDHHC8; zDHHC palmitoyltransferase 8

9 of 14

608784

ZDHHC9; zDHHC palmitoyltransferase 9

4 of 14

300646

INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED, SYNDROMIC, RAYMOND TYPE; MRXSR

syndromic X-linked intellectual disability Raymond type

ZDHHC14; zDHHC palmitoyltransferase 14

4 of 14

619295

ZDHHC18; zDHHC palmitoyltransferase 18

4 of 14

620963

ZDHHC19; zDHHC palmitoyltransferase 19

3 of 14

618671

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Zdhhc8

enhanceable

Ras64B

(Strassburger et al., 2019)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

58333

DroID - A comprehensive database of gene and protein interactions.

FBgn0085478

MIST (protein-protein) - An integrated Molecular Interaction Database

31887

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

HDL assembly

Class of Gene

gene_with_stop_codon_read_through

(Jungreis et al., 2011)

nuclear_gene

(FlyBase Genome Annotators, 2007)

protein_coding_gene

(FlyBase Genome Annotators, 2007)

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-27

Cytogenetic map

8D7-8D9

Sequence location

X:9,324,508..9,356,227 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

8D7-8D9

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-27

(FlyBase, 2016)

1-28.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (12)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

11925

w^67c23 P{lacW}Zdhhc8^G0250/FM7c

34413

y¹ w^* Mi{MIC}Zdhhc8^MI01245

43762

y¹ w^* Mi{MIC}Zdhhc8^MI01325

15044

y¹ w^67c23 P{EPgy2}Zdhhc8^EY00880

81987

y¹ sc^* v¹ sev²¹; P{TKO.GS04177}attP40

77705

y¹ w^* Mi{Trojan-GAL4.2}Zdhhc8^{MI01245-TG4.2}/FM7c

19156

w¹¹¹⁸ P{XP}Zdhhc8^d00976; l(3)*^*/TM6B, Tb¹

81398

y¹ sc^* v¹ sev²¹; P{SAM.dCas9.GS03942}attP40

Korea

10784

P{EP}Zdhhc8^G1376

NIG-Fly

HMJ22999

y¹ v¹; P{TRiP.HMJ22999}attP40/CyO

VDRC

v48025

w¹¹¹⁸ P{GD3540}v48025

v5521

w¹¹¹⁸; P{GD3294}v5521

Genomic Clones (18)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (6)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP01380

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0085478

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

GM06211

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0085478

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Strassburger et al., 2019)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Isolated from a pupal cDNA library, using a fragment of the fs(1)h coding region containing "pen" repetitive sequences (GGN, where N is any nucleotide) as the probe.

(Haynes et al., 1987)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG12136 CG15372 CG17251

(FlyBase Genome Annotators, 2002-2003)

Additional comments

Source for split of: CG32705

(FlyBase Genome Annotators, 2007)

Annotation CG32705 split into CG34449 and CG34450 in release 5.2 of the genome annotation.

(FlyBase Genome Annotators, 2007)

Annotations CG12136, CG15372, CG17251 merged as CG32705 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

"l(1)G0250" may affect "CG17251".

(Peter et al., 2002)

"l(1)G0346" may affect "CG17251".

(Peter et al., 2002)

Nomenclature History

Source for database identify of

Source for identity of: Zdhhc8 CG34449

(Strassburger et al., 2019)

Nomenclature comments

Etymology

Named 'Zdhhc8' based on orthology to human ZDHHC8.

(Strassburger et al., 2019)

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

CG12136

(FlyBase, 1992-)

CG15372

(FlyBase, 1992-)

CG17251

(Peter et al., 2002, FlyBase, 1992-)

CG32705

(Lin et al., 2010, Manak et al., 2006, Hoskins et al., 2005, Schneider et al., 2004, Giot et al., 2003)

CG34449

(Deng et al., 2023, National Institute of Genetics Fly Stocks, 2023-, Strassburger et al., 2019, Transgenic RNAi Project members, 2017-, Gene Disruption Project members, 2016-, Grice et al., 2015, Ashwal-Fluss et al., 2014, Garcia et al., 2013, Kwon et al., 2013, Hazelett et al., 2012, Praveen et al., 2012, Jungreis et al., 2011, Pessa et al., 2010, Bannan et al., 2008, FlyBase Genome Annotators, 2007)

Dm_X:47283

(FlyBase Genome Annotators, 2014, Ladoukakis et al., 2011)

Pen16

Zdhhc8

(Li et al., 2020, Maurer et al., 2020)

anon-Pen16

dZDHHC8

(Strassburger et al., 2019)

p16

(Haynes et al., 1987)

pen16

Name Synonyms

Zinc finger DHHC-type containing 8

Secondary FlyBase IDs

FBan0032705
FBgn0030129
FBgn0030128
FBgn0003058
FBgn0030127
FBgn0052705

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 44 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

31887

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9W345

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9W345

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

M9PH36

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9W345

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

31887/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085478

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085478

FlyMine - An integrated database for Drosophila genomics

FBgn0085478

InterPro - A database of protein families, domains and functional sites

Palmitoyltransferase, DHHC domain

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG34449

MARRVEL_MODEL - MARRVEL (model organism gene)

31887

Linkouts

BioGRID - A database of protein and genetic interactions.

58333

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0085478

DroID - A comprehensive database of gene and protein interactions.

FBgn0085478

DRSC - Results frm RNAi screens

FBgn0085478

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG34449_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085478

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0085478

Flygut - An atlas of the Drosophila adult midgut

FBgn0085478

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC002345

MIST (protein-protein) - An integrated Molecular Interaction Database

31887

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

HDL assembly

References (44)

The following external sites may use different assemblies or annotations than FlyBase.

-1.11

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