FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
hpo, mts
FlyBase ID
FBig0000086155
Interaction Network
Interactions Browser links
hpo network
mts network
Reported Interactions
FBrf0211636-4.coIP.MS
Reference
Ribeiro et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
hpo 

Hbo

bait

FLAG tag

mts 

Mts

prey

4 unique peptides identified

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Peptides for this prey protein have been found also in control AP-MS experiments, but were enriched in Cka and Mob4 purifications.

(Ribeiro et al., 2010)
FBrf0237510-9.coIP.WB
Reference
Zheng et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
mts 

Mts

bait

FLAG tag

hpo 

Hpo

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zheng et al., 2017)

The mts-hpo interaction is weak.

(Zheng et al., 2017)
FBrf0242574-1.coIP.WB
Reference
Gil-Ranedo et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
hpo 

Hippo

bait

FLAG tag

mts 

Mts

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from transfected construct.

(Gil-Ranedo et al., 2019)

Depletion of Mob4 and/or Cka decreases the hpo-mts interaction.

(Gil-Ranedo et al., 2019)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)