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Citation
Lai, Z.C., Rubin, G.M. (1992). Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein.  Cell 70(): 609--620.
FlyBase ID
FBrf0055572
Publication Type
Research paper
Abstract

Loss-of-function mutations in the yan gene result in the differentiation of supernumerary photoreceptors in the Drosophila eye. The yan gene encodes a protein with an ETS DNA-binding domain that accumulates in the nuclei of undifferentiated cells during the early stages of eye development. Our data suggest that yan functions as a cell-autonomous negative regulator of photoreceptor development; in the presumptive R7 and cone cells, yan appears to act antagonistically to the proneural signal mediated by sevenless and Ras1.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Aberrations (1)
    Alleles (13)
    Genes (10)
    Insertions (3)
    Transgenic Constructs (2)