FB2026_03 , released September 17, 2026
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Degtyarenko, K. (2000.9.19). Mitochondrial P450s in Drosophila. 
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FBrf0129623
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Personal communication to FlyBase
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Subject: mitochondrial P450s in Drosophila
 comments:    CYP12A4, CYP12A5, CYP12B2, CYP12C1, CYP12D1, CYP12E1, CYP301A1
    and CYP302A1 have more similarity to Musca domestica CYP12A1,
    which is a mitochondrial protein, and to mammalian mitochondrial
    P450s than to microsomal P450s. Therefore for these P450s
    'mitochondrial' is more plausible cellular location
    Source of information:
    1) Rene Feyereisen (personal communication)
    2) BLAST searches of the above proteins
    3) Guzov, V.M., Unnithan, G.C., Chernogolov, A.A. and Feyereisen, R.
       (1998) CYP12A1, a mitochondrial cytochrome P450 from the house fly.
       Arch. Biochem. Biophys. 359, 231-240.
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    English
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