Gene model reviewed during 5.48
In most Drosophila melanogaster strains tested, there is a single Cyp12d1 gene instead of two tandemly duplicated copies (FBrf0219004).
Cyp12d1-d and Cyp12d1-p derived from a tandem duplication of Cyp12d1 in the melanogaster group (FBrf0219004).
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cyp12d1-p using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Cyp12d1-p in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Two "Cyp12d1" genes are present in a tandem duplication at 47D; Cyp12d1-p (proximal) and Cyp12d1-d (distal). The release 3.2 annotations for these two genes are CG30489 (Cyp12d1-p) and CG33503 (Cyp12d1-d). Annotation CG30489 was labelled "CG18240" in release 2 of the genome annotation and "CG30489" in releases 3.0 and 3.1. Annotation CG33503 was labelled "CG18239" in release 2 of the genome annotation and "CG18240" in releases 3.0 and 3.1.
FlyBase curator comment: Figure 4 of FBrf0123240 lists "CYP12A2" associated with clone GM06292 (NCBI AA802777). That sequence is a ~100% BLAST hit to Cyp12d1-p and Cyp12d1-d, and that clone is linked to those two genes in FlyBase. On that basis, the 'Cyp12a2' (FBgn0040476) gene report has been obsoleted and 'CYP12A2' added as a synonym to Cyp12d1-p and Cyp12d1-d.