FB2025_01 , released February 20, 2025
Reference Report
Open Close
Reference
Citation
Gallant, P. (2013). Myc Function in Drosophila.  Cold Spring Harb. Perspect. Med. 3(10): .
FlyBase ID
FBrf0222931
Publication Type
Review
Abstract
Drosophila contains a single MYC gene. Like its vertebrate homologs, it encodes a transcription factor that activates many targets, including prominently genes involved in ribosome biogenesis and translation. This activity makes Myc a central regulator of growth and/or proliferation of many cell types, such as imaginal disc cells, polyploid cells, stem cells, and blood cells. Importantly, not only does Myc act cell autonomously but it also affects the fate of adjacent cells and tissues. This potential of Myc is harnessed by many different signaling pathways, involving, among others, Wg, Dpp, Hpo, ecdysone, insulin, and mTOR.
PubMed ID
PubMed Central ID
PMC3784813 (PMC) (EuropePMC)
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cold Spring Harb. Perspect. Med.
    Title
    Cold Spring Harbor perspectives in medicine
    ISBN/ISSN
    2157-1422
    Data From Reference
    Genes (9)