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Citation
McCall, K. (2004). Correction to Song et al. , Science 275 (5299) 536-540 and McCall and Steller, Science 279 (5348) 230-234.  Science 303(5661): 1138.
FlyBase ID
FBrf0225560
Publication Type
Erratum
Abstract
PubMed ID
PubMed Central ID
Related Publication(s)
Research paper

DCP-1, a Drosophila cell death protease essential for development.
Song et al., 1997, Science 275(5299): 536--540 [FBrf0092688]

Requirement for DCP-1 caspase during Drosophila oogenesis.
McCall and Steller, 1998, Science 279(5348): 230--234 [FBrf0100158]

Germline cell death is inhibited by P-element insertions disrupting the dcp-1/pita nested gene pair in Drosophila.
Laundrie et al., 2003, Genetics 165(4): 1881--1888 [FBrf0167648]

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Comments

"DCP-1, a Drosophila cell death protease essential for development" by Z. Song et al. (24 Jan. 1997, p. 536) and "Requirement for DCP-1 caspase during Drosophila oogenesis" by K. McCall and H. Steller (9 Jan. 1998, p. 230). Annotation of the Drosophila genome <up>M. D. Adams et al., Science287, 2185 (2000)</up> has shown that the dcp-1 gene is located within an intron of another gene, CG3941. P-element alleles of dcp-1 described in these two papers also disrupt expression of CG3941. Several phenotypes that were previously attributed to loss of dcp1, including melanotic tumors, small imaginal discs, and dumpless egg chambers, have now been shown to be due to disruption of CG3941 <up>B. Laundrie et al., Genetics 165, 1884 (2003)</up>. However, single mutations in dcp-1 show defective germline cell death, and loss of dcp-1 contributes to the ovary phenotype previously reported for the P-element alleles. Thus, the original ovary phenotype reported for the P-element alleles was due to the combined loss of dcp-1 and CG3941. The role of dcp-1 in somatic cell death is currently under investigation.

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Science
    Title
    Science
    Publication Year
    1895-
    ISBN/ISSN
    0036-8075 1095-9203
    Data From Reference
    Alleles (4)
    Genes (2)
    Insertions (2)