FB2026_03 , released September 17, 2026
Insertion: Dmel\P{Switch2}GSG176
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General Information
Symbol
Dmel\P{Switch2}GSG176
Species
D. melanogaster
Name
FlyBase ID
FBti0114998
Feature type
transposable_element_insertion_site
Description
Inserted Element
P{Switch2}
LINE ID
Affected gene(s)
RapGAP1, Scer\GAL4
Viability / fertility
viable
Associated allele(s)
Scer\GAL4GSG176
Stock availability
1 publicly available
Genomic Location
Chromosomal Location
2L ( 28B1 )
Sequence Location
2L:7,576,098..7,576,614
Target / Docking site
Genomic Maps
Member of Large Scale Dataset(s)
Dataset
Description
Detailed Mapping Data
Chromosome (arm)
Sequence Location
2L:7,576,098..7,576,614
(Cole et al., 2012.7.6)
Orientation
Cytological location (computed by FlyBase)
28B1 (inferred by FlyBase from sequence location)
Cytological location (reported)
28B1 (reported as inferred from sequence location)
(Nicholson et al., 2008, Nicholson et al., 2008)
28B1_r5 (reported as inferred from sequence location)
(Cole et al., 2012.7.6)
Insertion into Natural transposon
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct
P{Switch2}
(Nicholson et al., 2008)
Size (Kb)

7.931

(Roman, 2002.6.25)
Component Allele(s)
Molecular map
Affected Gene(s)
Insertion may affect gene
RapGAP1
(Nicholson et al., 2008)
Scer\GAL4
(Nicholson et al., 2008, Nicholson et al., 2008)
Variant Molecular Consequences
Phenotypic Data
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
larval neuron | subset of larval ventral nerve cord
(Nicholson et al., 2008)
larval neuron | subset of larval brain
(Nicholson et al., 2008)
CI fascicle
(Nicholson et al., 2008)
VM fascicle
(Nicholson et al., 2008)
motor neuron
(Nicholson et al., 2008)
embryonic/larval hypodermal muscle cell
(Nicholson et al., 2008)
embryonic/larval neuromuscular junction
(Nicholson et al., 2008)
embryonic/larval neuromuscular junction
(Nicholson et al., 2008)
ring gland
(Nicholson et al., 2008)
larval A1-7-innervating RP2 motor neuron
(Nicholson et al., 2008)
Additional Information
Statement
Reference

ScerGAL4GSG176 drives mifepristone-inducible expression primarily neuronally. Strong expression is observed in 4-5 cells per hemisegment at the dorsal midline of the ventral nerve cord; these include the A1-7 dorsal motor neurons. Stong ventral nerve cord expression is also oberved in ~10 lateral cells per hemisegment, and ~15 ventral cells per hemisegment, including 2-3 ventral midline cells per hemisegment; and along longitudinal intersegmental processes along the CI FasII fascicle, and along the VM fascicle. Weak expression is observed in a few cells in the brain hemispheres. Strong expression is observed in type Is and Ib boutons in the neuromuscular junctions of most muscle fibers. Expression is also observed in the ring gland. Very weak uninduced expression is observed in the salivary gland and in CNS dorsal midline cells.

(Nicholson et al., 2008)
 
Marker for
Reflects expression of
Reporter construct used in assay
Avic\GFP2x.EGFP.UAS
(Nicholson et al., 2008)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome
Related Aberration or Balancer
Aberration
Balancer
Stocks (1)
External Crossreferences and Linkouts ( 0 )
Comments
Comments

Insertion maps 5.3kb 5' of Spn7, 1.6kb 3' of CG13791 and 7.8kb 5' of Rapgap1 in antisense direction.

(Nicholson et al., 2008)
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
176
(Cole et al., 2012.7.6, Nicholson et al., 2008, Nicholson et al., 2008)
P{Switch2}GSG176
(FlyBase, 1992-)
Name Synonyms
Secondary FlyBase IDs
    References (4)