Cytoplasmic domain of Egfr is fused to the extracellular domain from a constitutively active mutant of tor. Expression is influenced by sev enhancer and an Hsp70 promoter.
Egfr intracellular kinase domain replaces the equivalent region from tor13D, expression of the chimera is driven by an Hsp70 promoter and a single copy of the 1.2kb sev enhancer.