FlyBase Allele Report: Dmel\kibra[EP666]

General Information

Symbol

Dmel\kibra^EP666

Species

D. melanogaster

Name

FlyBase ID

FBal0131391

Feature type

allele

Associated gene

Dmel\kibra

Associated Insertion(s)

P{EP}kibra^EP666

Carried in Construct

Also Known As

CG7552^EP666

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EP}kibra^EP666

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:14,723,812..14,723,812 [-]

(Baumgartner et al., 2010, Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^GMR.PF

(Müller et al., 2005)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

eye, with Scer\GAL4^GMR.PF

(Müller et al., 2005)

Detailed Description

Statement

Reference

Expression of CG33967^EP666 under the control of Scer\GAL4^GMR.PF results in a big eye phenotype.

(Müller et al., 2005)

Expression of CG33967^EP666 under the control of Scer\GAL4^ey.PH results in eyes that are slightly reduced in size. Flies expressing CG33967^EP666 under the control of Scer\GAL4^hs.2sev have wild-type eyes. Flies expressing CG33967^EP666 under the control of Scer\GAL4^en-e16E have wild-type wings.

(Tseng and Hariharan, 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, kibra^EP666 has visible phenotype, suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

kibra^EP666, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

kibra^EP666/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, kibra^EP666 has eye phenotype, suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

kibra^EP666, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

Other

Statement

Reference

Scer\GAL4^ap-md544, kibra^EP666, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, kibra^EP666, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, kibra^EP666, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^ap-md544, kibra^EP666, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing CG33967^EP666 under the control of Scer\GAL4^pnr-MD237 have a reduced scutellum. pnr^MD237/+ adults expressing CG33967^EP666 under the control of Scer\GAL4^ap-md544 have a slightly deformed scutellum.

(Pena-Rangel et al., 2002)

Co-expression of CycE^Scer\UAS.cLa suppresses the small eye phenotype caused by expression of CG33967^EP666 under the control of Scer\GAL4^ey.PH.

(Tseng and Hariharan, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG33967^EP666

CG7552^EP666

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002)

kibra^EP666

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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