FB2025_01 , released February 20, 2025
Allele: Dmel\upd1HMS00545
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General Information
Symbol
Dmel\upd1HMS00545
Species
D. melanogaster
Name
FlyBase ID
FBal0257234
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-upd1RNAi
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of upd1HMS00545 under the control of Scer\GAL4Cg.PA has no effect on either body weight or attraction to food cues in adult flies, whereas expression driven in the neural tissue by Scer\GAL4elav.PU heightens the attraction to food in fed flies so that it is comparable to the response observed in their starved counterparts as well as starved control flies (and higher than in fed controls). Scer\GAL4elav.PU>upd1HMS00545 flies also consume significantly more food, weigh more than controls and show increased fat deposition.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Upd1RNAi
UpdRNAi33680
osHMS00545
upd1HMS00545
Name Synonyms
Secondary FlyBase IDs
    References (11)