FB2025_01 , released February 20, 2025
Allele: Dmel\TuspUAS.cYa
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General Information
Symbol
Dmel\TuspUAS.cYa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Yoon
FlyBase ID
FBal0325063
Feature type
allele
Associated gene
Dmel\Tusp
Associated Insertion(s)
Carried in Construct
P{UAS-Tusp.Y}
Key Links
Transgenic product class
cDNA
(Yoon et al., 2017)
wild_type
(Yoon et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yoon et al., 2017)
wild_type
(Yoon et al., 2017)
Mutagen
in vitro construct
(Yoon et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Tusp.Y}
Cytology
Description

UASt regulatory sequences drive expression of a Tusp cDNA.

(Yoon et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Tusp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Tusp-G/TuspUAS.cYa rescues TuspG

      (Yoon et al., 2017)

      TuspUAS.cYa/Scer\GAL4shot-OK307 rescues Df(3R)Tusp-D

      (Yoon et al., 2017)

      TuspUAS.cYa/Scer\GAL4ChAT.7.4 rescues Df(3R)Tusp-D

      (Yoon et al., 2017)
      Fails to rescue

      Scer\GAL4DBD.R68A06, Hsap\RELAAD.R17A04, TuspUAS.cYa fails to rescue Df(3R)Tusp-D

      (Yoon et al., 2017)

      TuspUAS.cYa/Scer\GAL412862 fails to rescue Df(3R)Tusp-D

      (Yoon et al., 2017)

      Scer\GAL4shakB.lethal.4.1/TuspUAS.cYa fails to rescue Df(3R)Tusp-D

      (Yoon et al., 2017)

      Scer\GAL4VGlut1-OK371/TuspUAS.cYa fails to rescue Df(3R)Tusp-D

      (Yoon et al., 2017)

      Scer\GAL4Toll-6-D42/TuspUAS.cYa fails to rescue Df(3R)Tusp-D

      (Yoon et al., 2017)

      TuspUAS.cYa/Scer\GAL4C57 fails to rescue Df(3R)Tusp-D

      (Yoon et al., 2017)
      Comments

      The heat-shock induced paralytic phenotype characteristic for TuspG homozygous adults is rescued by expression of TuspScer\UAS.cYa under the control of Scer\GAL4Tusp-G (= the inherent TuspG Gal4). Expression under either Scer\GAL4shot-OK307 or Scer\GAL4ChAT.7.4 rescues the paralytic phenotype in the Df(3R)Tusp-D/Df(3R)Tusp-D deficiency mutants as well, while expression under any of the following neuronal drivers: Hsap\RELAAD.R17A04.T:Zzzz\Zip+ combined with Scer\GAL4DBD.R68A06.T:Zzzz\Zip-, Scer\GAL412862, Scer\GAL4shakB.lethal.4.1, Scer\GAL4VGlut-OK371, Scer\GAL4Toll-6-D42 or Scer\GAL4C57 fails to restore normal heat-shock resistance.

      (Yoon et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TuspScer\UAS.cYa
      TuspUAS.cYa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Yoon
      Secondary FlyBase IDs
        References (1)