FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(1)KA9
Open Close
General Information
Symbol
Df(1)KA9
Species
D. melanogaster
Name
FlyBase ID
FBab0000486
Feature type
chromosomal_deletion
Also Known As
KA9
Computed Breakpoints include

12E3;13A1

Features within 12E3--13A1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, Harris et al., 1996, Mitchell et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Oh et al., 1994, Palumbo et al., 1994, Drysdale et al., 1993, Drysdale et al., 1991, Leung et al., 1991, Kulkarni et al., 1988, Livingstone, 1985, Hardy et al., 1984, Livingstone et al., 1984, Deak et al., 1982, Mason et al., 1981, Craymer and Roy, 1980)
Breakpoints

12E1;13A5

(Livingstone, 1985, Hardy et al., 1984, Livingstone et al., 1984, Deak et al., 1982, Craymer and Roy, 1980)

12E6;13A5

(Mason et al., 1981)

12E1;12F1

(Palumbo et al., 1994)

12E3;13A5

(Schonbaum et al., 1995)

12E2-12E3;13A1

(Duffy et al., 1996)

12E6;13A2-13A5

(Mitchell et al., 1996)

12E2-12E3;12F5-13A1

(Harris et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Oh et al., 1994, Kulkarni et al., 1988)

12F2-12F3;12F5-13A1

(Drysdale et al., 1991)

12E2-12E3;12F-13A1

(Leung et al., 1991)

12E2-12E3;12F5-13A

(Drysdale et al., 1993)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

ben << bk1 << sesF << bk2 << eag

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0080375) Right limit of break 1 from polytene analysis (FBrf0048204) Left limit of break 2 from polytene analysis (FBrf0086390) Right limit of break 2 from polytene analysis (FBrf0048204)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Embryos hemizygous for Df(1)KA9 exhibit severe defects in the ventral nerve cord, with a near complete loss of midline crossing in some axon commissures; midline crossing of EW, EG and SP1 neurons is severely disrupted.

    (Cate et al., 2016)

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    The morphology of the proventriculus is normal in hemizygotes.

    (Kovalick et al., 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Embryos exhibit variable defects in the formation of commissural pathways. Scer\GAL4rho.PL induced expression of P{UAS-NETA} or P{UAS-NETB} significantly rescued the CNS phenotype.

    (Harris et al., 1996)

    CNS defect in embryos: axon commissures are drastically thinner or missing amd the longitudinal tracts are highly disorganised and discontinuous. Commissural phenotype is only weakly rescued by expression of P{slit-NetA} or P{slit-NetB}.

    (Mitchell et al., 1996)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Hemizygous embryos were examined with polarised light microscopy and antibody staining and found to have wild type muscle pattern and contraction.

    (Drysdale et al., 1993)

    incomplete condensation and splitting of ventral nerve cord in hemizygous embryos

    Stocks (1)
    Notes on Origin
    Discoverer

    Lefevre.

    (Livingstone, 1985)
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    References (40)