FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\In(1)sc8Lsc4R
Open Close
General Information
Symbol
In(1)sc8Lsc4R
Species
D. melanogaster
Name
Inversion (1) scute-8 Left scute-4 Right
FlyBase ID
FBab0004200
Feature type
inversion_derived_deficiency_plus_duplication
Also Known As
Df(1)sc8Lsc4R, In(1)sc8Lsc4R
Computed Breakpoints include
Features within h26--h32
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
In(1)sc8
In(1)sc4
Mutagen
recombination
Class of aberration (relative to wild type)
inversion_derived_deficiency_plus_duplication
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Ruiz-Gomez and Ghysen, 1993, Carramolino et al., 1982)

Deleted for 21 kb in y - sc (Carramolino et al., 1982)

Comments on Cytology

Duplicated for the NO.

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
bb
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    In(1)sc8Lsc4R/+ female often has crippled legs.

    NOT in combination with other aberrations

    10-15% of hemizygous males emerge from the pupal case. The number of bristles on the proboscis is reduced to 21 +/- 2. S-type and P-type bristles are unaffected, while some M-type and L-type bristles are missing. The labial disc lacks 10 sensory mother cells that are normally generated in the first two waves of specification.

    (Ray and Rodrigues, 1994)

    Hemizygous males show an almost complete loss of tergite chaetae.

    (Mari-Beffa et al., 1991)

    Eliminates ac expression from the notal clusters from which the sc dependent bristles arise.

    (Skeath and Carroll, 1991)

    In heterozygous females the deletion acts as a dominant suppressor of emc but not of h.

    (del Prado and Garcia-Bellido, 1984)

    homozygous female lethal Male survives rarely and is extreme sc and slight ac (Garcia-Bellido, 1979). Remains immobile after hatching.

    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    50-89% of In(1)sc8Lsc4R/+ adults lack upper humeral bristles.

    (Wrischnik et al., 2003)
    Synonyms and Secondary IDs (10)
    Reported As
    Symbol Synonym
    Df(1)sc8L4R
    (Skeath and Carroll, 1991)
    Df(1)sc8Lsc4R
    (Gomez-Skarmeta et al., 1995, Martin-Bermudo et al., 1993, Martinez and Modolell, 1991, Rodriguez et al., 1990)
    Dfsc8Lsc4R
    (Alonso and Cabrera, 1988)
    Dp(1;1)sc8Lsc4R
    In(1)sc8Lsc4R
    In(1)sc8Lsc4R
    (Wrischnik et al., 2003, Deshpande et al., 1995)
    In(1)sc8Lsc4R
    (Mari-Beffa et al., 1991)
    sc8L-4R
    (Ray and Rodrigues, 1994)
    sc8L-sc4R
    (Leyns et al., 1989)
    Name Synonyms
    Inversion (1) scute-8 Left scute-4 Right
    Secondary FlyBase IDs
      References (21)