FlyBase Allele Report: Dmel\Antp[23]

General Information

Symbol

Dmel\Antp²³

Species

D. melanogaster

Name

FlyBase ID

FBal0000564

Feature type

allele

Associated gene

Dmel\Antp

Associated Insertion(s)

F{}Antp²³

Carried in Construct

Also Known As

Antp^s1

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

X ray

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

Mutagen

X ray

(Scott et al., 1983)

Progenitor genotype

Associated Insertion(s)

F{}Antp²³

Cytology

Polytene chromosomes normal.

Description

Defective in promoter P2 function.

(Talbert and Garber, 1994)

Insertion of F-element at +134 in the DNA sequence corresponding to the P2 mRNA leader. This is within exon C, 1,261 bp upstream of the 1,134bp Antp ORFs.

(Laughon et al., 1986)

Insertion of an F-element at map position +162.

(Scott et al., 1983)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Antp^Scx)

(Southworth and Kennison, 2002)

lethal | recessive

(Talbert and Garber, 1994, Abbott and Kaufman, 1986, Scott et al., 1983)

lethal - all die before end of pupal stage | recessive

(Laughon et al., 1986)

some die during pupal stage | recessive

(Laughon et al., 1986)

viable (with Antp¹⁷)

(Southworth and Kennison, 2002)

viable (with Antp^73b)

(Southworth and Kennison, 2002)

viable (with Antp^B)

(Southworth and Kennison, 2002)

viable (with Antp^CB)

(Southworth and Kennison, 2002)

viable (with Antp^Ctx)

(Southworth and Kennison, 2002)

viable (with Antp^LC)

(Southworth and Kennison, 2002)

viable (with Antp^PW)

(Southworth and Kennison, 2002)

viable (with Antp^R)

(Southworth and Kennison, 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The penetrance of the held-out wing phenotype in Antp²³/Antp^B flies is increased if they are also heterozygous for brm².

(Vazquez et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

Antp^Ns-rv72

(Talbert and Garber, 1994)

Antp^Ns-rv11

(Talbert and Garber, 1994)

Antp^Ns-rv2

(Talbert and Garber, 1994)

Antp^Ns-rv86

(Talbert and Garber, 1994)

Partially complements

Antp^Ns-rvC11

(Talbert and Garber, 1994)

Antp^Ns-rvC8

(Talbert and Garber, 1994)

Antp^Ns-rvC6

(Talbert and Garber, 1994)

Antp^Ns-rvC2

(Talbert and Garber, 1994)

Fails to complement

Antp^Scx

(Southworth and Kennison, 2002)

Antp^Ns-rvC12

(Talbert and Garber, 1994)

Antp^Ns-rvC9

(Talbert and Garber, 1994)

Antp^Ns-rvC5

(Talbert and Garber, 1994)

Antp^Ns-rvC4

(Talbert and Garber, 1994)

Antp^Ns-rvC3

(Talbert and Garber, 1994)

Antp^Ns-rvC1

(Talbert and Garber, 1994)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

290

Antp²³ red¹ e¹/TM6B, Tb¹

Notes on Origin

Discoverer

Scott.

Comments

Complements: osa^Arv1

(Talbert and Garber, 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Antp²³

Antp^rS1

(Abbott and Kaufman, 1986)

Antp^s1

(Poliacikova et al., 2024, Bermingham et al., 1990, Laughon et al., 1986, Scott et al., 1983)

(Kaufman et al., 1990)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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