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General Information
Symbol
Dmel\br6
Species
D. melanogaster
Name
FlyBase ID
FBal0001193
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
brlt103, lt103
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Caused by aberration
Cytology
Nature of the lesion
Statement
Reference

Breakpoint at 146 to 151 kb.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The posterolateral medulla is fused with the adjacent lobula plate in hemizygous flies. Optic lobe position is abnormal.

Failure of salivary gland degeneration. Reduction in dorso-ventral class of indirect flight muscles. Some show proventriculus abnormality: foregut-midgut junction less proventriculus-like in appearance.

41% penetrance of abnormal SEG-TG separation phenotype, 55% of individuals show an abnormal optic lobe position and 35% a brain fusion failure.

'rbp' and br phenotype. Development of the early ecdysone puff in region 2B3--2B5 is not affected.

Lethal period is between pupal ecdysis and formation of the nonpigmented pupal legs and wings.

br6/br7 combination is lethal. Few adult escapers survive with short, broad wings. Adults of the br6/brrbp-3 or br6/brrbp-4 combination have reduced number of bristles on the palpus and have short, broad wings. Heterozygotes with Df(1)br25 have reduced viability and br wings.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially complements
Fails to complement
Comments

br6/+ x brnpr-6/+ crosses lead to transheterozygous males but no females being produced. Offspring die as pupae.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Deficient in 'rbp' function.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (14)