FlyBase Allele Report: Dmel\Delta[05151]

General Information

Symbol

Dmel\Delta⁰⁵¹⁵¹

Species

D. melanogaster

Name

FlyBase ID

FBal0002642

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

P{PZ}Delta⁰⁵¹⁵¹

Carried in Construct

Also Known As

Dl-lacZ, Delta-lacZ, Dl-LacZ⁰⁵¹⁵¹, P{PZ}Dl⁰⁵¹⁵¹

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}Delta⁰⁵¹⁵¹

Cytology

Description

The insertion is located 249 bp 5' to the Dl transcription unit.

(Mishra et al., 2001)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:19,326,218..19,326,218 [+]

(Calderon et al., 2022, Reddy et al., 2022, Zeng et al., 2010, Campbell, 2005, Wang and Struhl, 2004, Mishra et al., 2001, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates ataxia telangiectasia

modeled by tefu^RNAi.UAS

(Rimkus et al., 2008)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

visible | dominant

(He et al., 2005)

Phenotype Manifest In

metatarsus (with Delta^blX59)

(Mishra et al., 2001)

tarsal segment 2 (with Delta^blX59)

(Mishra et al., 2001)

tarsal segment 3 (with Delta^blX59)

(Mishra et al., 2001)

tarsal segment 4 (with Delta^blX59)

(Mishra et al., 2001)

wing vein

(He et al., 2005)

Detailed Description

Statement

Reference

Multiple photoreceptor-R8 cells are not observed in eye tissue from Dl⁰⁵¹⁵¹/+ animals.

(Steele et al., 2009)

Heterozygous flies have an expanded wing vein phenotype.

(He et al., 2005)

Compound tarsus seen in T1-4 when over Dl^blX59.

(Mishra et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Delta⁰⁵¹⁵¹ has visible phenotype, enhanceable by Df(3L)81k19/+

(He et al., 2005)

Delta⁰⁵¹⁵¹ has visible phenotype, enhanceable by Mo25[+]/Mo25⁰⁰²⁷⁴

(He et al., 2005)

Enhancer of

Statement

Reference

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of increased cell number | third instar larval stage | somatic clone phenotype of rno¹

(Steele et al., 2009)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of increased cell number | third instar larval stage | somatic clone phenotype of Rbf^15aΔ, rno¹

(Steele et al., 2009)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Suppressor of

Statement

Reference

Delta⁰⁵¹⁵¹/Dl[+] is a suppressor of lethal | recessive | partially | embryonic stage phenotype of peb³⁰⁸

(Wilk et al., 2004)

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta⁰⁵¹⁵¹ has wing vein phenotype, enhanceable by Df(3L)81k19/+

(He et al., 2005)

Delta⁰⁵¹⁵¹ has wing vein phenotype, enhanceable by Mo25[+]/Mo25⁰⁰²⁷⁴

(He et al., 2005)

Enhancer of

Statement

Reference

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of photoreceptor cell R8 | third instar larval stage | somatic clone phenotype of rno¹

(Steele et al., 2009)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of photoreceptor cell R8 | third instar larval stage | somatic clone phenotype of Rbf^15aΔ, rno¹

(Steele et al., 2009)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PU, tefu^RNAi.UAS

(Rimkus et al., 2008)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, tefu^RNAi.UAS

(Rimkus et al., 2008)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of eye photoreceptor cell phenotype of Scer\GAL4^GMR.PU, tefu^RNAi.UAS

(Rimkus et al., 2008)

Delta⁰⁵¹⁵¹/Dl[+] is an enhancer of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

The multiple photoreceptor-R8 phenotype seen in rno¹ or rno¹, Rbf^15aΔ eye somatic mutant clones is significantly increased in a Dl⁰⁵¹⁵¹/+ background.

(Steele et al., 2009)

Dl⁰⁵¹⁵¹/+ enhances the rough-eye phenotype and reduces the number of normal photoreceptors per ommatidium in flies expressing tefu^{dsRNA.Scer\UAS} under the control of Scer\GAL4^GMR.PU. Increased incidence of ommatidium fusions are observed in these animals.

(Rimkus et al., 2008)

The expanded wing vein phenotype seen in Dl⁰⁵¹⁵¹/+ flies is enhanced by Mo25⁰⁰²⁷⁴/+ and by Df(3L)81k19/+.

(He et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Delta^L9254c

(BDGP Project Members, 1994-1999)

Delta^j8C3

(BDGP Project Members, 1994-1999)

Delta⁰⁶⁶⁰⁶

(BDGP Project Members, 1994-1999)

Delta⁰³⁹⁸⁰

(BDGP Project Members, 1994-1999)

Delta⁰³⁹³⁵

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: l(3)03675⁰³⁷⁵⁰. Complements: l(3)05050⁰⁵⁰⁵⁰. Complements: Vha13⁰⁵¹¹³. Complements: l(3)05820⁰⁵⁸²⁰. Complements: bnl⁰⁶⁹¹⁶. Complements: l(3)neo51¹.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Delta⁰⁵¹⁵¹

Dl⁰⁵¹⁵¹

(Ozdowski et al., 2009)

Dl^P05151

(He et al., 2005)

delta⁰⁵¹⁵¹

(Calderon et al., 2022)

l(3)05151

(Spradling et al., 1999)

Name Synonyms

Delta05151

(Rimkus et al., 2008)

Secondary FlyBase IDs

References (15)

Report Sections

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