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General Information
Symbol
Dmel\peb308
Species
D. melanogaster
Name
FlyBase ID
FBal0126346
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hnt308
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
transposable element insertion site
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The P{hsp70-boss} insertion is located 509bp upstream of the peb cDNA NB701, with the 5' of the element closest to the peb exon.

Insertion components
P{hsp70-boss}peb308
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

peb308 mutants exhibit 41% embryonic lethality. 19.6% of embryos exhibit a germband retraction phenotype, 65.6% a dorsal closure phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

peb308 has lethal | embryonic stage | partially | recessive phenotype, enhanceable by chic[+]/chic221

peb308 has lethal | embryonic stage | partially | recessive phenotype, enhanceable by kst[+]/kst01318

peb308 has lethal | embryonic stage | partially | recessive phenotype, enhanceable by vkg[+]/vkgk00236

peb308 has lethal | embryonic stage | partially | recessive phenotype, enhanceable by vkg[+]/vkgk07138

peb308 has lethal | embryonic stage | partially | recessive phenotype, enhanceable by vkg[+]/vkgk16721

NOT Enhanced by
Statement
Reference

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by puc1/puc[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by pucA251.1F3/puc[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by slbory8/slbo[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by vkg[+]/vkgk16502

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by Rho1k07236/Rho1[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by chic[+]/chic01320

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by heixk11403/heix[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by kst[+]/kst1

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-enhanceable by kst[+]/kst2

Suppressed by
Statement
Reference

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by Cg25C[+]/Col4a1k00405

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by Dl05151/Dl[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by LanA3A1/LanA[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by LanA4A8/LanA[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by tkvk16713/tkv[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by tutlk14703/tutl[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by vkg[+]/vkg01209

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by vkg177/vkg[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by Rho1J3.8/Rho1[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, suppressible by Cg25C[+]/Col4a1234

NOT suppressed by
Statement
Reference

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by Rho1k07236/Rho1[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by chic[+]/chic01320

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by heixk11403/heix[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by kst[+]/kst1

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by kst[+]/kst2

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by puc1/puc[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by pucA251.1F3/puc[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by slbory8/slbo[+]

peb308 has lethal | embryonic stage | partially | recessive phenotype, non-suppressible by vkg[+]/vkgk16502

Phenotype Manifest In
Enhanced by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The addition of bskJ27 or bsk1 suppresses the lethality phenotype seen in peb308 embryos, leading to 29% and 18% lethality respectively. The addition of dpp10638 suppresses the lethality phenotype seen in peb308 embryos, leading to 5% lethality. The addition of dppP23 enhances the phenotypes seen in peb308 embryos, leading to 80% lethality, 40.5% of embryos exhibiting a germband retraction phenotype, and 50.2% a dorsal closure phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)