FlyBase Allele Report: Dmel\vkg[k07138]

General Information

Symbol

Dmel\vkg^k07138

Species

D. melanogaster

Name

FlyBase ID

FBal0046696

Feature type

allele

Associated gene

Dmel\vkg

Associated Insertion(s)

P{lacW}vkg^k07138

Carried in Construct

Also Known As

vkg^BLK

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Rodriguez et al., 1996)

Progenitor genotype

Associated Insertion(s)

P{lacW}vkg^k07138

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Rodriguez et al., 1996)

Phenotype Manifest In

egg chamber (with vkg⁰¹²⁰⁹)

(Díaz de la Loza et al., 2017)

Detailed Description

Statement

Reference

Lethality occurs during embryonic and larval stages. Newly hatched larvae are rounded, slow moving and short lived.

(Rodriguez et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

vkg[+]/vkg^k07138 is an enhancer of lethal | embryonic stage | recessive | partially phenotype of peb³⁰⁸

(Wilk et al., 2004)

NOT Enhancer of

Statement

Reference

vkg[+]/vkg^k07138 is a non-enhancer of visible | dominant phenotype of sog^EP7

(Araujo et al., 2003)

vkg[+]/vkg^k07138 is a non-enhancer of visible | dominant phenotype of sog^EP11

(Araujo et al., 2003)

Suppressor of

Statement

Reference

vkg[+]/vkg^k07138 is a suppressor of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

NOT Suppressor of

Statement

Reference

vkg[+]/vkg^k07138 is a non-suppressor of visible | dominant phenotype of sog^EP11

(Araujo et al., 2003)

vkg[+]/vkg^k07138 is a non-suppressor of visible | dominant phenotype of sog^EP7

(Araujo et al., 2003)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

vkg[+]/vkg^k07138 is a non-enhancer of wing vein phenotype of sog^EP7

(Araujo et al., 2003)

vkg[+]/vkg^k07138 is a non-enhancer of wing vein phenotype of sog^EP11

(Araujo et al., 2003)

Suppressor of

Statement

Reference

vkg[+]/vkg^k07138 is a suppressor of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

NOT Suppressor of

Statement

Reference

vkg[+]/vkg^k07138 is a non-suppressor of wing vein phenotype of sog^EP11

(Araujo et al., 2003)

vkg[+]/vkg^k07138 is a non-suppressor of wing vein phenotype of sog^EP7

(Araujo et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Shows only 6% malformed phenotype when heterozygous in combination with zip^Ebr/+.

(Halsell and Kiehart, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

vkg¹⁷⁷

(Wilk et al., 2004)

vkg^k00236

(Wilk et al., 2004)

vkg^k16502

(Wilk et al., 2004)

vkg⁰¹²⁰⁹

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

102534

y¹ w^67c23 ; P{lacW}vkg^k07138 / CyO

Notes on Origin

Discoverer

I. Kiss.

Comments

Mobilisation of P{lacW} reverts the lethal phenotype demonstrating the insertion causes the mutant phenotype. Level of Ecol\lacZ expression and viability of adults is not altered by bacterial infection of adults.

(Rodriguez et al., 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

71/38

(Rodriguez et al., 1996)

vkg^BLK

(Araujo et al., 2003, Halsell and Kiehart, 1998, Kimbrell, 1996.4.28, Rodriguez et al., 1996)

vkg^K07138

(Díaz de la Loza et al., 2017)

vkg^k07138

(Matsubayashi et al., 2020)

Name Synonyms

Secondary FlyBase IDs

FBal0043366

References (9)

Report Sections

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