FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pnut02502
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General Information
Symbol
Dmel\pnut02502
Species
D. melanogaster
Name
FlyBase ID
FBal0008001
Feature type
allele
Associated gene
Dmel\pnut
Associated Insertion(s)
P{PZ}pnut02502
Carried in Construct
Also Known As
l(2)02502
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}pnut02502
Cytology
Description

P{PZ} insertion in exon 1.

(Schnorr et al., 2001)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Huntington's disease
      modeled by Hsap\HTT128Q.1-336.UAS
      (Kaltenbach et al., 2007)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Moderate dominant enhancer of the Ras85Dix12a eggshell phenotype; 31-40% of dorsal appendages are wild type.

      (Schnorr et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      pnut02502 is an enhancer of abnormal cell polarity phenotype of S48-5

      (Gaengel and Mlodzik, 2003)
      Suppressor of
      Statement
      Reference

      pnut02502 is a suppressor of visible phenotype of Hsap\HTT128Q.1-336.UAS, Scer\GAL4GMR.PU

      (Kaltenbach et al., 2007)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      pnut02502 is an enhancer of ommatidium phenotype of S48-5

      (Gaengel and Mlodzik, 2003)

      pnut[+]/pnut02502 is an enhancer of dorsal appendage phenotype of Ras85Dix12a

      (Schnorr et al., 2001)
      NOT Enhancer of
      Statement
      Reference

      pnut[+]/pnut02502 is a non-enhancer of mitotic domain 1 | embryonic cycle 14 phenotype of CycB+t10

      (Ji et al., 2002)
      Suppressor of
      Statement
      Reference

      pnut02502 is a suppressor of eye phenotype of Hsap\HTT128Q.1-336.UAS, Scer\GAL4GMR.PU

      (Kaltenbach et al., 2007)
      NOT Suppressor of
      Statement
      Reference

      pnut[+]/pnut02502 is a non-suppressor of mitotic domain 1 | embryonic cycle 14 phenotype of CycB+t10

      (Ji et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      S48-5/pnut02502 mutants show 20.07%+-11.25 misrotated ommatidia compared to 9.55%+-1.43 seen in S48-5 mutants alone.

      (Gaengel and Mlodzik, 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: kermit02045. Complements: l(2)k03110k02203. Complements: l(2)k03110k03110. Complements: l(2)k03110k04002. Complements: l(2)k07521k07521. Complements: Rs1k09514.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      02502
      (Kaltenbach et al., 2007)
      l(2)02502
      (Schnorr et al., 2001, Spradling et al., 1999)
      l(2)0250202502
      peanut-02502
      (Gaengel and Mlodzik, 2003)
      pnut02502
      Name Synonyms
      Secondary FlyBase IDs
        References (9)