FlyBase Allele Report: Dmel\kuz[k01403]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\kuz^k01403

General Information

Symbol

Dmel\kuz^k01403

Species

D. melanogaster

Name

FlyBase ID

FBal0008401

Feature type

allele

Associated gene

Associated Insertion(s)

P{lacW}kuz^k01403

Carried in Construct

Also Known As

l(2)k01403, kuz¹⁴⁰³

Key Links

Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Rooke et al., 1996)

Mutagen

P-element activity

(Roch et al., 1998, Sotillos et al., 1997, Rooke et al., 1996)

Progenitor genotype

Associated Insertion(s)

P{lacW}kuz^k01403

Cytology

Description

Insertion of a P{lacW} element within untranslated leader sequences.

(Sotillos et al., 1997)

P{lacW} insertion within either the first intron or the first exon.

(Rooke et al., 1996)

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

reporter enzyme

Tagged with

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:13,550,212..13,550,212 [+]

(Koelzer and Klein, 2006, Koelzer and Klein, 2003, Ashburner et al., 1999, Ashburner et al., 1999, Ashburner et al., 1999.10.12, Spradling et al., 1999, Roch et al., 1998, Sotillos et al., 1997, Rooke et al., 1996, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Ashburner et al., 1999, Spradling et al., 1999, Roch et al., 1998)

Phenotype Manifest In

(Roch et al., 1998, Sotillos et al., 1997)

Detailed Description

Statement

Reference

The neuromuscular innervation pattern appears normal in kuz^e29-4/kuz^k01403 larvae.

(Meyer and Aberle, 2006)

Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities. In tergites, clones with normal size and frequency are recovered. Clones cannot be recovered in the wing disc.

(Roch et al., 1998)

Homozygous larvae have imaginal discs similar in size and shape to those of kuz^k01405 homozygous larvae.

(Sotillos et al., 1997)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

(Sotillos et al., 1997)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

kuz⁰³⁷⁸²

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

10505

y¹ w^67c23; P{lacW}kuz^k01403/CyO

60690

w¹¹¹⁸; Df(2R)IR52a-d, P{lacW}kuz^k01403 PBac{RB5.WH5}IR52a-d/CyO

102204

y¹ w^67c23 ; P{lacW}kuz^k01403 / CyO

Notes on Origin

Discoverer

I. Kiss.

May be a cluster mate of kuz^k01405.

(Ashburner et al., 1999.10.12)

Comments

Comments

Complements: l(2)05337⁰⁵³³⁷. Complements: Sos^k05224. Complements: RpII33^k05605. Complements: l(2)k06917^k06917. Complements: l(2)k12004^k12004. Complements: l(2)k14817^k14817.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

14/3

(Roch et al., 1998)

k01403

(Ashburner et al., 1999)

kuz¹⁴⁰³

(Koelzer and Klein, 2006, Koelzer and Klein, 2003)

kuz^K01403

(Meyer and Aberle, 2006)

kuz^k01403

l(2)k01403

(Spradling et al., 1999, Sotillos et al., 1997, Rooke et al., 1996)

l(2)k01403^k01403

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections