FlyBase Allele Report: Dmel\Phb1[20]

General Information

Symbol

Dmel\Phb1²⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0008763

Feature type

allele

Associated gene

Dmel\Phb1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

diepoxybutane

Nature of the Allele

Allele class

Mutagen

diepoxybutane

Progenitor genotype

Cytology

Description

100bp intragenic deletion.

(Stathakis et al., 1995)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | adult stage | somatic clone

(Zhao et al., 2022)

Phenotype Manifest In

adult posterior midgut epithelium | somatic clone

(Zhao et al., 2022)

Detailed Description

Statement

Reference

Most adulthood-induced Phb1²⁰ clones in the intestine contain only one cell; upon DSS-induced regeneration clones also contain only one cell.

(Zhao et al., 2022)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by Atg1^HMS02750/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by scu^UAS.Exel/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by Phb2^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by dind^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by Scer\GAL4^Act5C.PI/Hsap\PHB2^UAS.Tag:V5

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by Scer\GAL4^Act5C.PI/Atg5^HMS01244

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | adult stage | somatic clone phenotype, non-enhanceable by Scer\GAL4^Act5C.PI/bmm^UAS.mCherry

(Zhao et al., 2022)

Suppressed by

Statement

Reference

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, suppressible | partially by E2f1^UAS.cNa/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, suppressible | partially by Scer\GAL4^Act5C.PI/Hsap\PHB1^UAS.Tag:V5

(Zhao et al., 2022)

NOT suppressed by

Statement

Reference

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by dind^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by Phb2^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by Scer\GAL4^Act5C.PI/Hsap\PHB2^UAS.Tag:V5

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by Atg1^HMS02750/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by Scer\GAL4^Act5C.PI/Atg5^HMS01244

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by Scer\GAL4^Act5C.PI/bmm^UAS.mCherry

(Zhao et al., 2022)

Phb1²⁰ has decreased cell number | somatic clone | adult stage phenotype, non-suppressible by scu^UAS.Exel/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Suppressor of

Statement

Reference

Phb1²⁰/Phb1²⁰ is a suppressor of increased cell number | somatic clone | adult stage phenotype of Egfr^2.A887T.UAS, Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰/Phb1²⁰ is a suppressor of increased cell number | somatic clone | adult stage phenotype of Scer\GAL4^Act5C.PI, hop^Tum.UAS

(Zhao et al., 2022)

Phb1²⁰/Phb1²⁰ is a suppressor of increased cell number | somatic clone | adult stage phenotype of Raf^UAS.F179, Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by Atg1^HMS02750/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by scu^UAS.Exel/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by Phb2^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by dind^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by Scer\GAL4^Act5C.PI/Hsap\PHB2^UAS.Tag:V5

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by Scer\GAL4^Act5C.PI/Atg5^HMS01244

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-enhanceable by Scer\GAL4^Act5C.PI/bmm^UAS.mCherry

(Zhao et al., 2022)

Suppressed by

Statement

Reference

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, suppressible | partially by E2f1^UAS.cNa/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, suppressible | partially by Scer\GAL4^Act5C.PI/Hsap\PHB1^UAS.Tag:V5

(Zhao et al., 2022)

NOT suppressed by

Statement

Reference

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by Atg1^HMS02750/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by Scer\GAL4^Act5C.PI/Atg5^HMS01244

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by Scer\GAL4^Act5C.PI/Hsap\PHB2^UAS.Tag:V5

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by Scer\GAL4^Act5C.PI/bmm^UAS.mCherry

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by scu^UAS.Exel/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by Phb2^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰ has adult posterior midgut epithelium | somatic clone phenotype, non-suppressible by dind^UAS.Tag:FLAG/Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Suppressor of

Statement

Reference

Phb1²⁰/Phb1²⁰ is a suppressor of adult posterior midgut epithelium | somatic clone phenotype of Egfr^2.A887T.UAS, Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Phb1²⁰/Phb1²⁰ is a suppressor of adult posterior midgut epithelium | somatic clone phenotype of Scer\GAL4^Act5C.PI, hop^Tum.UAS

(Zhao et al., 2022)

Phb1²⁰/Phb1²⁰ is a suppressor of adult posterior midgut epithelium | somatic clone phenotype of Raf^UAS.F179, Scer\GAL4^Act5C.PI

(Zhao et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Phb1²⁰ is rescued by Scer\GAL4^Act5C.PI/Phb1^UAS.Tag:V5

(Zhao et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

5389

Phb1²⁰ pr¹/CyO

Kyoto

108199

Phb1²⁰ pr¹/CyO

Notes on Origin

Discoverer

Cecil.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Phb1²⁰

(Zhao et al., 2022)

l(2)37Cc²⁰

l(2)DEB12

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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