FlyBase Allele Report: Dmel\l(3)j5B6[j5B6]

General Information

Symbol

Dmel\l(3)j5B6^j5B6

Species

D. melanogaster

Name

FlyBase ID

FBal0010968

Feature type

allele

Associated gene

l(3)j5B6

Associated Insertion(s)

P{lacW}l(3)j5B6^j5B6

Carried in Construct

Also Known As

l(3)j5B6

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{lacW}l(3)j5B6^j5B6

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:8,766,382..8,766,382 [+]

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

l(3)j5B6^j5B6/l(3)j5B6[+] is a non-enhancer of visible | dominant phenotype of Egfr^E1

(Read et al., 2005)

Suppressor of

Statement

Reference

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of visible phenotype of Dys^RNAi.NH2.UAS, Scer\GAL4^Act.PU

(Kucherenko et al., 2008)

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of visible phenotype of Dys^RNAi.C.UAS, Scer\GAL4^Tub.PU

(Kucherenko et al., 2008)

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of visible phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of visible phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

NOT Suppressor of

Statement

Reference

l(3)j5B6^j5B6/l(3)j5B6[+] is a non-suppressor of visible | dominant phenotype of Egfr^E1

(Read et al., 2005)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

l(3)j5B6^j5B6/l(3)j5B6[+] is a non-enhancer of eye phenotype of Egfr^E1

(Read et al., 2005)

Suppressor of

Statement

Reference

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of posterior crossvein phenotype of Dys^RNAi.NH2.UAS, Scer\GAL4^Act.PU

(Kucherenko et al., 2008)

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of posterior crossvein phenotype of Dys^RNAi.C.UAS, Scer\GAL4^Tub.PU

(Kucherenko et al., 2008)

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of eye phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

l(3)j5B6^j5B6/l(3)j5B6[+] is a suppressor of eye phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

NOT Suppressor of

Statement

Reference

l(3)j5B6^j5B6/l(3)j5B6[+] is a non-suppressor of eye phenotype of Egfr^E1

(Read et al., 2005)

Other

Statement

Reference

Dys^RNAi.C.UAS, l(3)j5B6^j5B6/l(3)j5B6[+] has wing vein | ectopic phenotype

(Kucherenko et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

One copy of l(3)j5B6^j5B6 moderately suppresses the detached posterior crossvein phenotype seen when Dys^{dsRNA.NH2.Scer\UAS} is expressed under the control of Scer\GAL4^Act.PU.

One copy of l(3)j5B6^j5B6 weakly suppresses the detached posterior crossvein phenotype seen when Dys^{dsRNA.C.Scer\UAS} is expressed under the control of Scer\GAL4^tub.PU but produces extra wing vein material.

(Kucherenko et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

12073