Open Close
General Information
Symbol
Dmel\w1
Species
D. melanogaster
Name
FlyBase ID
FBal0018074
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
w
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a Doc element.

Insertion of a 5.7kb Doc element.

Insertion of Doc element at +3700bp.

Doc element inserted into w promoter region.

Insertion of Doc element into the proximal region of w.

Insertion of 4.9kb Doc element, close to the site of transcription initiation. 13bp of w sequence from +3700 to +3688 is duplicated, and is present at both ends of the Doc insertion (nucleotide positions as in FBrf0041384). The Doc element is inserted in the same orientation as the direction of w transcription.

5kb Doc insert at +3.71; Origin = insertion of wa copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Insertion components
Doc{}w1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant males display negligible intermale courtship upon recurring ethanol administration with 70% ethanol, in contrast to wild-type males which show intermale courtship after repeated ethanol exposure.

Homozygotes have white eyes with only <1% red pigment (compared to 100% pigment in wild type).

Bleach white eyes.

Eye colour: wsp1/w1 flies have brown eyes at eclosion, which become somewhat darker with age.

White eye colour, suppresses z1.

Eye colour: white. Ocellus colour: colourless. Testis colour: colourless. Malpighian tubule colour: colourless.

Eye colour: bleach white.

Eye colour: The wcf2 eye colour is not diluted when wcf2 is in transheterozygous combination with w1.

Eye colour: wdil/w1 flies have darker eyes than g1 and lighter eyes than pn1.

Eye colour: white. Ocellus colour: colourless. Testis colour: colourless. Malpighian tubule colour: colourless. Eye colour: brown at eclosion, darker after 4-5 days, as w1/wsp1.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

w1/we(g) is an enhancer of eye color defective phenotype of g53d

w1/we(g) is an enhancer of eye color defective phenotype of g2

w1/we(g) is an enhancer of eye color defective phenotype of g50e

Other
Statement
Reference
Phenotype Manifest In
NOT suppressed by
Statement
Reference

w1 has phenotype, non-suppressible by su(Hw)2

Enhancer of
Statement
Reference

w1/we(g) is an enhancer of pigment cell phenotype of g53d

w1/we(g) is an enhancer of pigment cell phenotype of g2

w1/we(g) is an enhancer of pigment cell phenotype of g50e

Suppressor of
Statement
Reference

w1 is a suppressor of phenotype of z1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Flies with a w1/we(g) mutant genotype enhance the eye colour defective phenotype of g2, g50e and g53d homozygous mutants leading to a greater reduction of red pigment in the eye.

A suppressor of the repression on w by z1.

w1 su(f)4/wa su(f)1 females have a w1 phenotype at 24-25oC. wa su(f)4/Y males have an eye colour intermediate between that of w1 and wa at 17-18oC.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Complements
Partially complements
Rescued by
Partially rescued by

w1 is partially rescued by w+tAR

w1 is partially rescued by w+mC

w1 is partially rescued by wHSBJ

Comments
Images (2)
Stocks (674)
Notes on Origin
Discoverer

Morgan, March 1910.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (61)